… focused on targeting BRAF as an … and clinical features of BRAF mutant colorectal cancer,
the prognostic and predictive role of BRAFV600E mutation in colorectal cancer, initial clinical …

… of PTC, and the clinical implications of BRAFV600E mutation in the diagnosis, prognosis …
its clinical implications.In this article, we review the mechanism of BRAFV600E mutation and …

… On these bases, BRAF mutational testing is now … are needed to further stratify patients
carrying this mutation. … -V600E BRAF mutations, which accounts for 22% of all BRAF …

… of BRAF mutations has emerged. … on BRAF mutation status: BRAF V600E- and non-V600-mutated
CRC [13]. These two molecular subtypes of CRC are characterized by distinct clinical …

… the BRAF mutation in terms of prognostic and clinical implications, and although this
mutation occurs in varied genetic backgrounds, its presence can influence clinical practice and …

… to do clinical studies on the correlation between BRAF mutation and … BRAF should be
considered. We propose studies in CRC in Iran on the clinical impact of KRAS and BRAF mutation, …

… of BRAF mutation with the clinical progression, recurrence, and treatment failure of PTC has
also been demonstrated. The BRAF mutation has … mechanisms determining BRAF mutation-…

… of most non-V600E BRAF mutations is increased compared with WT BRAF receptor activity,
but some BRAF mutations are kinase-dead or have lower activity than WT BRAF [Wan et al. …

… role of BRAF mutations in melanoma and colorectal cancer, focusing on similarities and
differences of BRAF mutations with respect to frequency, demographics, risk factors, mutation-…

… of rare V600 BRAF mutations in primary tumours and different metastases of melanoma
patients, compares different detection methods, and correlates the BRAF genotype with clinical …