Glycosylation in cancer: mechanisms and clinical implications

SS Pinho, CA Reis - Nature Reviews Cancer, 2015 - nature.com
… of cancer cells. The most-widely occurring changes in glycosylation associated with cancer
… Aberrant glycosylation in cancer frequently involves an increase in sialyl Lewis x (SLe x ) …

Glycosylation and its implications in breast cancer

DA Scott, RR Drake - Expert review of proteomics, 2019 - Taylor & Francis
… This review will address the role of glycosylation in breast cancer carcinogenesis … clinical
implications and utility of analyzing changes in serum glycosylation patterns for breast cancer

Aberrant protein glycosylation in cancer: implications in targeted therapy

JG Rodrigues, HO Duarte, CA Reis… - Biochemical Society …, 2021 - portlandpress.com
… may further improve the clinical performance of currently approved anti-cancer targeted
agents. In this review, we highlight the impact of glycosylation in cancer targeted therapy, with …

[HTML][HTML] Glycosylation in cervical cancer: new insights and clinical implications

Z Xu, Y Zhang, DKW Ocansey, B Wang, F Mao - Frontiers in Oncology, 2021 - frontiersin.org
… gynecological cancer process, especially cervical cancer. With … glycosylation and concentrates
on how cancer-associated glycans affect the tumor microenvironment. The implications

Glycosylation of cancer extracellular vesicles: capture strategies, functional roles and potential clinical applications

ÁM Martins, CC Ramos, D Freitas, CA Reis - Cells, 2021 - mdpi.com
… in cancer and … clinical application of the EV glycosylation in anti-cancer therapy and in the
discovery of new biomarkers for the prognosis and early diagnosis of different types of cancer

Glycosylation in cancer: its application as a biomarker and recent advances of analytical techniques

Y Haga, K Ueda - Glycoconjugate Journal, 2022 - Springer
… Aberrant glycosylation is well defined as a hallmark of cancer and represents a promising …
us to analyze cancer-specific glycoforms on a target protein in a variety of clinical samples. A …

Protein glycosylation alterations in hepatocellular carcinoma: function and clinical implications

Y Wang, H Chen - Oncogene, 2023 - nature.com
… glycomic signatures could be used to predict the response to anti-cancer therapy. Here
we summarize the potential clinical implications of altered glycosylation in HCC (Table 1). …

Glycosylation of immunoglobin G in tumors: Function, regulation and clinical implications

S Yang, M Cui, Q Liu, Q Liao - Cancer Letters, 2022 - Elsevier
… is involved in all stages of tumor development, and glycosylation-programmed antibodies
have … glycosylation occurring in IgG and reveals the clinical significance of glycosylated IgG. …

Evolutional and clinical implications of the epigenetic regulation of protein glycosylation

T Horvat, V Zoldoš, G Lauc - Clinical Epigenetics, 2011 - Springer
… Protein N glycosylation is an ancient posttranslational … all the genes involved in N glycosylation.
Due to the absence of … from differences in protein glycosylation. However, composition of …

Glycosylation markers in cancer

A Silsirivanit - Advances in clinical chemistry, 2019 - Elsevier
… and glycoproteins as well as their roles in cancer would likely facilitate diagnosis and
treatment. In this chapter, the alteration of protein glycosylation and the role of tumor-associated …