Altered glycosylation in tumours focused to cancer diagnosis

R Peracaula, S Barrabés, A Sarrats, PM Rudd… - Disease …, 2008 - content.iospress.com
… in clinical practice reveals that many of them are glycoproteins, including glycosylated
Considering that in tumour situation cancer cells use non-normal or “aberrant” glycosylation for …

Human T cell glycosylation and implications on immune therapy for cancer

E De Bousser, L Meuris, N Callewaert… - Human Vaccines & …, 2020 - Taylor & Francis
… role of glycosylation of human T cells in more depth, elaborate on the importance of
glycosylation in the interaction of human T cells with tumor cells and discuss the potential of cancer

[HTML][HTML] The role of N-glycosylation in cancer

Y Lin, DM Lubman - Acta Pharmaceutica Sinica B, 2023 - Elsevier
glycosylation in a tumor is essential for comprehending disease progression and discovering
anti-cancer … of protein N-glycosylation and summarizes glycosylation changes in tumor cells…

[HTML][HTML] Glycosylation changes in prostate cancer progression

W Butler, J Huang - Frontiers in Oncology, 2021 - frontiersin.org
… many cancer settings including PCa. Aberrant glycosylation is a well-known hallmark of cancer
… In this review, we summarize the wide range of glycosylation changes observed as PCa …

Altered glycosylation of proteins produced by malignant cells, and application for the diagnosis and immunotherapy of tumours

A Kobata, J Amano - Immunology and cell biology, 2005 - Wiley Online Library
… In this review, current knowledge of the altered N-glycosylation of glycoproteins produced
in tumour cells will be summarized to help readers to consider the importance of this topic. …

Glycosylation changes in cancer

SL Bellis, CA Reis, A Varki, R Kannagi, P Stanley - 2022 - europepmc.org
… Altered glycosylation is a universal feature of cancer cells, and certain glycans are well-… in
cancer cells; correlations between altered glycosylation, diagnosis, and clinical prognosis; the …

[HTML][HTML] The role of N-glycans in colorectal cancer progression: Potential biomarkers and therapeutic applications

JCM de Freitas Junior, JA Morgado-Díaz - Oncotarget, 2016 - ncbi.nlm.nih.gov
glycosylation, which is one of the most common protein post-translational modifications, are
considered to be a hallmark of cancer. … colorectal cancer (CRC) is a leading cause of cancer-…

[HTML][HTML] Glycosylation in the tumor microenvironment: implications for tumor angiogenesis and metastasis

KB Chandler, CE Costello, N Rahimi - Cells, 2019 - ncbi.nlm.nih.gov
… Hypoxia and inflammatory events regulate protein glycosylation in tumor cells and … anti-cancer
therapeutics. In this review, we highlight the impact of altered glycosylation on angiogenic …

Glycosylation of biosimilars: Recent advances in analytical characterization and clinical implications

BL Duivelshof, W Jiskoot, A Beck, JL Veuthey… - Analytica chimica …, 2019 - Elsevier
glycosylation is considered a crucially important quality attribute, because of its major role
in immunogenicity and clinical … to illustrate the potential clinical implications of differences in …

[HTML][HTML] The hidden potential of glycomarkers: Glycosylation studies in the service of cancer diagnosis and treatment

K Grzesik, M Janik, D Hoja-Łukowicz - … Acta (BBA)-Reviews on Cancer, 2023 - Elsevier
… Detected in serum, the abundantly glycosylated cancer marker A1AT possesses three N-glycosylation
sites (N70, N107, and N271) and forms various isoforms (isoA1AT) with molecular …