Protein glycosylation in gastric and colorectal cancers: Toward cancer detection and targeted therapeutics

JA Ferreira, A Magalhaes, J Gomes, A Peixoto… - Cancer letters, 2017 - Elsevier
… to unravel the complex nature of cancer-associated glycosylation. Nevertheless, key structural
… -specific nature of cancer-associated glycans and its clinical implications in large and well …

Branched N-glycans and their implications for cell adhesion, signaling and clinical applications for cancer biomarkers and in therapeutics

N Taniguchi, H Korekane - BMB reports, 2011 - koreascience.kr
… -glycosylation sites such as Asn 772 caused the constitutive activation of this proteinase and
this may enhance cancer … in cancer metastasis. They also found that TIMP-1 was aberrantly …

Glycosylation in the tumor microenvironment: implications for tumor angiogenesis and metastasis

K Brown Chandler, C E. Costello, N Rahimi - Cells, 2019 - mdpi.com
… Hypoxia and inflammatory events regulate protein glycosylation in tumor cells and … anti-cancer
therapeutics. In this review, we highlight the impact of altered glycosylation on angiogenic …

[PDF][PDF] Mechanisms of cancer-associated glycosylation changes

F Dall'Olio, N Malagolini, M Trinchera… - Front Biosci, 2012 - article.imrpress.com
… changes is crucial in the perspective of therapeutic interventions aimed at the normalization
of the glycosylation pattern of cancer cells. Cancer-associated glycosylation changes are in …

[HTML][HTML] Sweet and sour: the impact of differential glycosylation in cancer cells undergoing epithelial–mesenchymal transition

L Freire-de-Lima - Frontiers in oncology, 2014 - frontiersin.org
… component expressed by cancer cells and … glycosylation changes, we may benefit from
understanding how unusual glycans can govern the molecular pathways associated with cancer

Clinic implication of MUC1 O-glycosylation and C1GALT1 in esophagus squamous cell carcinoma

Y Wang, X Liao, Q Ye, L Huang - Science China Life Sciences, 2018 - Springer
… -glycosylated MUC1 in ESCC, not only suggesting a diagnostic significance of C1GALT1 and
MUC1 O-glycosylation in … in pancreatic cancer which indicated that glycosylation of MUC1 …

[HTML][HTML] Altered tumor-cell glycosylation promotes metastasis

I Häuselmann, L Borsig - Frontiers in oncology, 2014 - frontiersin.org
… generation of cancer-specific glycans (2). Altered glycosylation of N-linked glycans in cancer
is … However, the functional role of branched N-glycosylation in cancer was later shown to be …

Glycoproteins: their structure, biosynthesis and possible clinical implications

H Schachter - Clinical biochemistry, 1984 - Elsevier
… and the initial glycosylation occurs either while the peptide is still nascent on the ribosome
or shortly after translation has been completed. Initial glycosylation involves transfer of …

Glycosylation and antitumor immunity

AP Cadena, TR Cushman, JW Welsh - International Review of Cell and …, 2019 - Elsevier
… the glycosylation pathway have been intricately linked with the development of cancer and
more recently with cancer's … This chapter aims to elucidate how glycosylation interacts with the …

[HTML][HTML] Roles of glycosylation at the cancer cell surface: opportunities for large scale glycoproteomics

T Čaval, F Alisson-Silva, F Schwarz - Theranostics, 2023 - ncbi.nlm.nih.gov
glycosylation status. Here we provide an overview of the broad changes in glycosylation at
the surface of cancer … of receptors with aberrant glycosylation leading to functional changes, …