BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications

KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
… the pathogenesis of PTC, and the clinical implications of … its tumorigenic role and its
clinical implications.In this article, … of PTC, the clinical implications of BRAFV600E mutation in …

BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

M Xing - Endocrine reviews, 2007 - academic.oup.com
pathogenic role of this mutation in PTC, which has led to great enthusiasm in recent years
over the potential clinical … with an emphasis on its pathogenic role, underlying molecular bases…

Human papillomavirus in head and neck cancer: its role in pathogenesis and clinical implications

CH Chung, ML Gillison - Clinical cancer research, 2009 - AACR
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with
an annual incidence of approximately 400,000 worldwide. Although the principal risk factors …

Pathogenesis of idiopathic pulmonary fibrosis and its clinical implications

P Spagnolo, G Rossi, A Cavazza - Expert review of clinical …, 2014 - Taylor & Francis
… In particular, TGF-β, the production of which is predominantly sustained by activated
macrophages, plays a key pathogenetic role by promoting epithelial-mesenchymal transition, …

Autoimmunity in primary immunodeficiency disorders: an updated review on pathogenic and clinical implications

G Costagliola, S Cappelli, R Consolini - Journal of Clinical Medicine, 2021 - mdpi.com
… they may have a pathogenic role. Additionally, lower naïve CD4+ and CD8+ T cells and
increased differentiated T cells have been described in CVID patients with autoimmunity [18]. …

Hepatitis C virus genetic variability: pathogenic and clinical implications

JM Pawlotsky - Clinics in liver disease, 2003 - liver.theclinics.com
… may have important consequences on the pathogenesis of infection and related diseases. …
the molecular basis of HCV genetic variability and its pathogenic and clinical implications. …

The molecular pathogenesis and clinical implications of hepatocellular carcinoma

M Meguro, T Mizuguchi, M Kawamoto… - International journal of …, 2011 - Wiley Online Library
… In this review, we describe the molecular pathogenesis and the current state and future
development of molecular- and CSC-therapeutic targeted agents for HCC, citing various reports. …

Membranous nephropathy: new pathogenic mechanisms and their clinical implications

E Hoxha, L Reinhard, RAK Stahl - Nature Reviews Nephrology, 2022 - nature.com
… MN, focusing on the evidence for their pathogenic role in disease initiation, differences and
… their potential clinical impact. Lastly, we explore the clinical implications of the pathogenic

Molecular pathways: pathogenesis and clinical implications of microbiome alteration in esophagitis and Barrett esophagus

L Yang, F Francois, Z Pei - Clinical Cancer Research, 2012 - AACR
pathogens or pathogens, and pathogen-associated molecular patterns, use distinct
signaling pathways that eventually converge to activate NF-κB, leading to the production of …

hepatitis C virus‐associated steatosis–pathogenic mechanisms and clinical implications

LE Adinolfi, E DURANTE‐MANGONI… - Alimentary …, 2005 - Wiley Online Library
… The presence of a significant amount of steatosis (ie >20%) in CHC patients has major
clinical implications. A growing body of evidence suggests that steatosis has a central role in the …