… treatment options existed for patients with chronic myeloid leukemia (CML): IFN and stem
cell transplantation (SCT). IFN, although effective and even curative in some patients, 1 had …

… An earlier phase I study of patients with CML in all phases found that the response rate was
… Thus, in the phase II study in AP, patients were initially treated with a starting dose of 400 mg…

… defining leukemogenic event in chronic myelogenous leukemia (CML) revolutionized the …
for the first-line treatment of patients with chronic-phase CML because of its high long-term …

… treatment paradigms in chronic phase CML. The discussion of … it improves patients’ quality
of life, frees patients from chronic … to chronic phase CML as accelerated and blast phase CML …

… Although allogeneic SCT from siblings is the best chance for cure for CML patients in chronic
phase, only 15% to 20% of patients are candidates for this treatment given the limitations of …

… Imatinib mesylate given orally at a daily dose of 400 mg is the standard of care as initial
therapy for patients with chronic myeloid leukemia (CML) in chronic phase (CML‐CP). Treatment …

… which may keep patients with CML in chronic phase indefinitely. This has created a situation
in which patient monitoring is essential for detecting changes in the status of CML. The tests …

… We conclude that nilotinib is an effective initial therapy for patients with CML in early chronic
phase, with a high rate of response and rapid achievement of CCyR in nearly all patients …

… Experimental Design: We analyzed the results of quantitative PCR in 280 patients with CML
in chronic phase who achieved complete cytogenetic remission with imatinib (117 after IFN-…

… patients receiving autografts in chronic phase is longer than that of conventionally treated
control patients … patients in chronic phase by autografting (Rarnett rt a/. 1989; De Fabritiis et ul, …