Urban particulate matter in air pollution penetrates into the barrier-disrupted skin and produces ROS-dependent cutaneous inflammatory response in vivo

SP Jin, Z Li, EK Choi, S Lee, YK Kim, EY Seo… - Journal of …, 2018 - Elsevier
skin. Repeated PM application induced epidermal thickening and dermal inflammation with
… Finally, N-acetyl cysteine could ameliorate skin inflammation induced by PM application. …

Urban particulate matter down-regulates filaggrin via COX2 expression/PGE2 production leading to skin barrier dysfunction

CW Lee, ZC Lin, SCS Hu, YC Chiang, LF Hsu, YC Lin… - Scientific reports, 2016 - nature.com
… We demonstrated in vivo that the inhibitor AhRI, as well as apocynin (a specific inhibitor
of Nox2), suppressed PM-induced inflammatory responses in skin by inhibiting COX-2 …

Air pollution and skin diseases: Adverse effects of airborne particulate matter on various skin diseases

KE Kim, D Cho, HJ Park - Life sciences, 2016 - Elsevier
immune responses, including enhanced lung inflammation due to increasing various pro-…
and dermal inflammation. Immunologically, Th17 cells are dominant in psoriatic skin lesions, …

Skin inflammation induced by ambient particulate matter in China

Y Dong, L Liao, L Li, F Yi, H Meng, Y He… - Science of the Total …, 2019 - Elsevier
… to skin inflammation as well as inflammatory skin diseases, such as atopic dermatitis, acne,
eczema, and skin … useful information for future research on PM-induced skin inflammation. …

Impact of airborne particulate matter on skin: A systematic review from epidemiology to in vitro studies

IM Dijkhoff, B Drasler, BB Karakocak… - Particle and fibre …, 2020 - Springer
Particulate matter was shown to induce a skin barrier … activation of the inflammatory cascade
in human skin. Moreover, a … and pro-inflammatory response were substantially stronger …

Associations of particulate matter with atopic dermatitis and chronic inflammatory skin diseases in South Korea

TH Park, S Park, MK Cho, S Kim - Clinical and experimental …, 2022 - academic.oup.com
… the skin, inducing cutaneous inflammatory responses. Based on these features, PM seems
to cause or exacerbate various skin … AD is a chronic inflammatory skin disease caused by …

[HTML][HTML] Particulate matter induces inflammatory cytokine production via activation of NFκB by TLR5-NOX4-ROS signaling in human skin keratinocyte and mouse skin

YS Ryu, KA Kang, MJ Piao, MJ Ahn, JM Yi, YM Hyun… - Redox biology, 2019 - Elsevier
… Ambient air pollution has become a major worldwide problem; especially, fine particulate
matter … can trigger an inflammatory response in the respiratory system and may lead to systemic …

[HTML][HTML] Particulate matter causes skin barrier dysfunction

BE Kim, J Kim, E Goleva, E Berdyshev, J Lee… - JCI insight, 2021 - ncbi.nlm.nih.gov
… Epithelial barrier dysfunction induces type 2 immune responses and is considered an
initial step in developing atopic dermatitis (AD) and the atopic march (14, 16, 17). Epidermal …

[HTML][HTML] Air particulate matter induces skin barrier dysfunction and water transport alteration on a reconstructed human epidermis model

DS Hieda, LA da Costa Carvalho, BV de Mello… - Journal of Investigative …, 2020 - Elsevier
… We confirmed an inflammatory process by IL-1α release and found a significant … process.
These results demonstrate that coarse air PM induces dose-dependent inflammatory response

[HTML][HTML] Role of particulate matter in skin inflammation

M Arooj, YS Koh - Journal of Bacteriology and Virology, 2019 - synapse.koreamed.org
particulate matter and its effects on health. Here we have summarized that particulate matter
… human health especially on skin and cause different skin inflammatory conditions. Further …