Although survival of individuals with cystic fibrosis (CF) has been continuously improving for
the past 40 years, respiratory failure secondary to recurrent pulmonary infections remains …

… with more advanced airway disease have high levels … of CF patients, the Cystic Fibrosis
Foundation has initiated a … for Disease Control before the launch of the Cystic Fibrosis …

… The aims of this article are to summarize existing knowledge regarding the pathophysiology
of small airways disease in cystic fibrosis (CF), to speculate about additional mechanisms …

… Cystic fibrosis (CF) lung disease is manifested by unrelenting bacterial infections of airway …
functions of normal airway epithelia and how they are deranged in cystic fibrosis. As shown in …

… cystic fibrosis transmembrane conductance regulator (CFTR) at the apical membrane of airway
… Cystic fibrosis is a multi-organ disease that reflects the consequences of mutations in the …

… Alcaligenes xylosoxidans isolated from patients with Cystic Fibrosis, along with an increase
… samples of Cystic Fibrosis patients in the Regional Referral Cystic Fibrosis Centre of Naples…

… Following the discovery of the cystic fibrosis transmembrane conductance regulator (CFTR)
gene in 1989, the structure and function of the CFTR protein were described. Since then, …

… in pigs also show that deficiency of CFTR-mediated transport of bicarbonate and regulation
of the pH of airway surface liquid inhibits antimicrobial function in the cystic fibrosis airways. …

… by the formation of endobronchial mucus plaques and plugs, which become the main sites
of air flow obstruction, infection, and inflammation conducing to early small airways disease …

… IL-17 levels are elevated in the sputum of adult patients with cystic fibrosis (CF) undergoing
… and hypertonic saline on airway inflammation in children with cystic fibrosis. Am J Respir …