… of the disease. This review focuses on the lung involvement in cystic fibrosis and summarizes
new … of CF and pathogenesis of related lung disease. Current therapeutic modalities, novel …

… This concept also is congruent with the failure of exogenous antimicrobial agents, eg as
part of the chronic therapy for CF lung disease, to be curative, as reviewed elsewhere in this …

… cystic fibrosis (CF), the pathogenesis of CF lung disease remains obscure. The elucidation of
the pathogenesis of CF lung disease … of the cystic fibrosis transmembrane regulator protein (…

… the lung disease. Respiratory disease such as that in humans does not develop in mice with
cftr mutations. However, lung disease that mimics that in humans with cystic fibrosis occurs …

… Cystic fibrosis lung disease is characterized by early colonization and infection of the … and
predicts the development of bronchiectasis later in life [4]. No other lung disease is known to …

… to explain why we are still struggling to understand CF lung disease. The pattern of CF lung
disease is unlike that of any other lung disease. In CF, infections of the smaller airways are …

… Progressive lung disease in cystic fibrosis (CF) is the life-limiting factor of this autosomal …
of CF lung disease, hence longitudinal imaging is recommended for disease monitoring in the …

Rationale: Cystic fibrosis (CF) is characterized by bronchoalveolar neutrophilia and submucosal
lymphocytosis. We hypothesized that Th17 lymphocytes are part of this submucosal …

… of cystic fibrosis lung disease. We summarise the current knowledge and the methods used
to characterise and quantify early lung disease. … lung disease in patients with cystic fibrosis. …

… Pseudomonas aeruginosa infection in cystic fibrosis. Diagnostic … cystic fibrosis lung.
Microbiology 1999;145:1349–1357. 16. … with azithromycin on disease parameters in cystic fibrosis: …