[HTML][HTML] Tissue specific differentially methylated regions (TDMR): Changes in DNA methylation during development

F Song, S Mahmood, S Ghosh, P Liang, DJ Smiraglia… - Genomics, 2009 - Elsevier
methylation analysis was used to confirm and determine the fine structure of tissue specific
differences in DNA methylation… possibility that the methylation differences reflect expansion of …

DNA methylation profiling identifies global methylation differences and markers of adrenocortical tumors

NS Rechache, Y Wang, HS Stevenson… - The Journal of …, 2012 - academic.oup.com
… other genome content of the differentially methylated probe sites in the comparisons again
showed that although the total number of differentially methylated sites is lowest in benign …

Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility

LE Reinius, N Acevedo, M Joerink, G Pershagen… - PloS one, 2012 - journals.plos.org
… 1) to identify differentially methylated CpG sites … differences in DNA methylation between
lymphoid and myeloid cells and identified many CpG sites that were differentially methylated

DNA methylation-based variation between human populations

F Kader, M Ghai - Molecular genetics and genomics, 2017 - Springer
… Not only has DNA methylation differences shown to impact … Differential DNA hypermethylation
in promoters occurred … women; hypermethylated differentially methylated CpGs in African …

Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

B Zhang, Y Zhou, N Lin, RF Lowdon, C Hong… - Genome …, 2013 - genome.cshlp.org
… an unprecedented opportunity to map DNA methylation differences between tissues and cells
… Here, we introduce a novel statistical framework, “M&M,” to detect differentially methylated

Substantial DNA methylation differences between two major neuronal subtypes in human brain

A Kozlenkov, M Wang, P Roussos… - Nucleic acids …, 2016 - academic.oup.com
… Next, we identified CpH sites that were differentially methylated between the GABA and
GLU neurons, using a threshold of [|delta (β)| > 0.1] and FDR-corrected P-value < 0.05. In …

Epigenetics: differential DNA methylation in mammalian somatic tissues

H Nagase, S Ghosh - The FEBS journal, 2008 - Wiley Online Library
DNA methylation patterns at 4600 NotI sites and more than 150 differentially methylated
A deeper understanding of cell-type-specific differences in DNA methylation might lead to a …

DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy

C Sapienza, J Lee, J Powell, O Erinle, F Yafai… - Epigenetics, 2011 - Taylor & Francis
… We also believe it is significant that MTHFR is identified as a differentially methylated
gene in ESRD patients on HD. MTHFR is a central node in the one-carbon metabolism pathway,12,…

DNA methylation contributes to natural human variation

H Heyn, S Moran, I Hernando-Herraez… - Genome …, 2013 - genome.cshlp.org
… Consistently, we aimed to determine DNA methylation differences between human populations
… To define CpG sites that are differentially methylated between populations, we excluded …

Quantitative comparison of genome-wide DNA methylation mapping technologies

C Bock, EM Tomazou, AB Brinkman, F Müller… - Nature …, 2010 - nature.com
… immunoprecipitation sequencing (MeDIP-seq), methylated DNA capture by affinity … DNA
methylation data. However, these methods differ in their ability to detect differentially methylated