Self emulsifying drug delivery system for enhanced solubility and dissolution of glipizide

AG Agrawal, A Kumar, PS Gide - Colloids and Surfaces B: Biointerfaces, 2015 - Elsevier
… This decrease was attributed to the enhanced solubility and dissolution rate of GPZ from
S-SEDDS which resulted in improved bioavailability of the drug. From the results, it was evident …

[HTML][HTML] Design, optimization and evaluation of glipizide solid self-nanoemulsifying drug delivery for enhanced solubility and dissolution

RN Dash, H Mohammed, T Humaira… - Saudi Pharmaceutical …, 2015 - Elsevier
… to improve the solubility and dissolution profile of glipizide. SNEDDS … The saturation solubility
(SS) of glipizide in optimized … leading to an enhanced solubility and dissolution of glipizide. …

[PDF][PDF] Comparative dissolution study of glipizide by solid dispersion technique

MHG Dehghan, M Saifee… - Journal of pharmaceutical …, 2010 - academia.edu
… the solubility and dissolution of Glipizide in water by solid dispersion. The solid dispersion of
glipizide was prepared using water soluble … the solubility and dissolution rate of Glipizide- a …

[PDF][PDF] Enhancement of the dissolution rate and bioavailability of Glipizide

AM Aly, MK Qato, MO Ahmad - Pharm technol, 2003 - alfresco-static-files.s3.amazonaws …
Glipizide (GZ) is a widely used oral hypoglycemic drug with very poor water solubility.The
purpose of this study was to enhance the dissolution rate and bioavailability of this drug. To …

Formulation and evaluation of solid dispersion of glipizide for solubility and dissolution rate enhancement

A Gupta, MK Kataria, A Bilandi - International Journal of Pharmaceutics …, 2014 - neliti.com
… the oral bioavailability of active agents include enhancing solubility and dissolution rate of
poorly water soluble drugs & enhancing permeability of poorly water-soluble drugs. One of the …

[PDF][PDF] Formulation and evaluation of solid dispersions of glipizide for dissolution rate enhancement

MR Shivalingam, T Jyothibasu, YVK Reddy… - Int. J. Pharma. Res …, 2011 - academia.edu
… :carrier shows better phase solubility and invitro dissolution rate. … techniques are available
to enhance the solubility of drug like … was made to enhance the drug solubility by using solvent …

Solubility Enhancement of Glipizide and Development of its Fast-dissolving Oral Film

HA Pawar, MSMA Momin - Current Drug Therapy, 2021 - ingentaconnect.com
… dispersion of the glipizide showed improved solubility by almost 10 folds. Many of the formulated
films … Conclusion: The solubility of Glipizide was improved successfully by solubilization …

Role of surfactant and pH on dissolution properties of fenofibrate and glipizide—a technical note

S Jamzad, R Fassihi - Aaps Pharmscitech, 2006 - Springer
… quality assessments, in the evaluation of the rate of dissolution for 2 low solubility drugs,
glipizide and fenofibrate. The influence of formulation, sink conditions, surfactant type, and …

Solid carriers for improved solubility of glipizide in osmotically controlled oral drug delivery system

A Mehramizi, B Alijani, M Pourfarzib… - Drug development …, 2007 - Taylor & Francis
solubility and dissolution rate of gli by solid dispersion technique using PVP in EOP tablets…
Glipizide is poor water-soluble and weak acid with a pK of 5.9 with a pH-dependent solubility (…

Enhancing the Bioavailability of Glipizide by Solid Dispersion

UD Shivhare, VI Ramteke, VB Mathur… - Research Journal of …, 2010 - indianjournals.com
dissolution rates compared to pure glipizide and physical mixture of glipizide with polyethylene
glycol and glipizide … saturation solubility of glipizide explains the improved dissolution of …