Mitochondrial DNA content affects the fertilizability of human oocytes

P Reynier, P May-Panloup, MF Chretien… - Molecular human …, 2001 - academic.oup.com
… that mitochondrial DNA content could play a role in oocyte fertilizability. A significant reduction
in mtDNA content was observed in oocytes from group 2 in comparison with oocytes from …

DNA damage and repair in human oocytes and embryos: a review

Y Ménézo, B Dale, M Cohen - Zygote, 2010 - cambridge.org
… In this review we focus on the expression of mRNAs that regulate DNA repair capacity in
the human oocyte and the mechanisms that protect the embryo against de novo damage. …

Fertilization and embryology: The early development and DNA content of activated human oocytes and parthenogenetic human embryos

AS Taylor, PR Braude - Human reproduction, 1994 - academic.oup.com
DNA content using a computerized image analysis system showed that activated oocytes with
one pronudeus had a DNA contentoocytes to replicate their DNA was also demonstrated. …

Mitochondrial DNA rearrangements in human oocytes and embryos

JA Barritt, CA Brenner, J Cohen… - Molecular Human …, 1999 - academic.oup.com
… of human oocytes or embryos that contained mtDNA rearrangements. Significant reductions
in the number of oocytes … to determine the ATP content of human oocytes in association with …

Low oocyte mitochondrial DNA content in ovarian insufficiency

P May-Panloup, MF Chretien, C Jacques… - Human …, 2005 - academic.oup.com
DNA (mtDNA) in 116 oocytes obtained from 47 women undergoing the ICSI procedure. We
compared the mtDNA content of oocytes … ) ATP content of human oocytes and developmental …

Assessment of the cellular DNA content of whole mounted mouse and human oocytes and of blastomeres containing single or multiple nuclei

NJ Winston, MH Johnson, PR Braude - Zygote, 1993 - cambridge.org
… the case with human oocytes and embryos. … DNA content in both live and fixed mouse
oocytes and blastomeres, (including multinucleated cells) and on whole-mounted human oocytes

Mitochondrial DNA content and 4977 bp deletion in unfertilized oocytes

CCW Chan, VWS Liu, EYL Lau… - Molecular human …, 2005 - academic.oup.com
… in unfertilized oocytes in relation to donors’ age have been controversial… oocytes and relate
them to the donors’ age. Fifty-two women donated 155 unfertilized metaphase II (MII) oocytes

[HTML][HTML] The association of reproductive senescence with mitochondrial quantity, function, and DNA integrity in human oocytes at different stages of maturation

HE Duran, F Simsek-Duran, SC Oehninger… - Fertility and sterility, 2011 - Elsevier
content of oocytes increases in parallel with maturational stage. It is generally believed that
human oocytes … the increase in ATP content by advancing oocyte maturational stage that we …

Mitochondrial DNA deletion in human oocytes and embryos.

CA Brenner, YM Wolny, JA Barritt… - Molecular human …, 1998 - academic.oup.com
DNA (mtDNA) deletions are present in both human oocytes … deletion was investigated in
human oocytes and embryos. … of the KSS deletion in 74 human oocytes and 137 embryos was …

Expression profiling of DNA repair genes in human oocytes and blastocysts using microarrays

S Jaroudi, G Kakourou, S Cawood, A Doshi… - Human …, 2009 - academic.oup.com
… Subsequent to this, DNA repair is expected to have a major impact on embryo development.
human oocytes express DNA repair genes at high levels allowing low tolerance for DNA