[HTML][HTML] DNA demethylation dynamics

N Bhutani, DM Burns, HM Blau - Cell, 2011 - cell.com
… capable of mediating DNA demethylation in mammalian cells. These findings raise the
possibility that regulation by DNA methylation is at times quite dynamic, providing exciting …

Modeling DNA methylation profiles through a dynamic equilibrium between methylation and demethylation

G De Riso, DFG Fiorillo, A Fierro, M Cuomo, L Chiariotti… - Biomolecules, 2020 - mdpi.com
… We also observed a prevalence of independent DNA demethylation in Condition 15. …
Using a modeling approach, we explored the DNA methylation and demethylation dynamics in …

[PDF][PDF] DNA demethylation dynamics in the human prenatal germline

S Gkountela, KX Zhang, TA Shafiq, WW Liao… - Cell, 2015 - cell.com
DNA demethylation during development in vivo occurs in the germline. In humans, there is
limited information on the dynamics of DNA demethylation … extensive DNA demethylation than …

Dynamics of DNA demethylation

T Nawy - Nature Methods, 2013 - go.gale.com
… "We now come to realize that DNA methylation is not static," says He. Rather, much of the
genome exists as "a dynamic equilibrium of methylation and demethylation." DNA methylation …

TET enzymes, TDG and the dynamics of DNA demethylation

RM Kohli, Y Zhang - Nature, 2013 - nature.com
… advanced our understanding of DNA demethylation. 5-Hydroxymethylcytosine is a key nexus
in demethylation that can either be passively depleted through DNA replication or actively …

Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine

JA Hackett, R Sengupta, JJ Zylicz, K Murakami, C Lee… - Science, 2013 - science.org
… and genome-wide DNA demethylation to reset the epigenome for … that escape systematic
DNA demethylation in PGCs, … —including global DNA demethylation, chromatin reorganization, …

Potential functional roles of DNA demethylation intermediates

CX Song, C He - Trends in biochemical sciences, 2013 - cell.com
demethylation process. Interestingly, emerging evidence indicates that these DNA demethylation
intermediates are dynamic … 5caC as new epigenetic DNA modifications that could have …

Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes

M Wossidlo, J Arand, V Sebastiano, K Lepikhov… - The EMBO …, 2010 - embopress.org
… X strand breaks and DNA demethylation further, we analysed the dynamics of both at the …
First, we had to determine the extent and dynamics of DNA demethylation in cloned embryos at …

Alteration of DNA demethylation dynamics by in vitro culture conditions in rabbit pre-implantation embryos

AR Reis e Silva, C Bruno, R Fleurot, N Daniel… - Epigenetics, 2012 - Taylor & Francis
… For this reason, we focused our comparisons on the dynamics of DNA demethylation both
in vivo and in vitro. Our quantitative data evidenced a gradual demethylation in IVD and IVC …

Dynamics and biological relevance of DNA demethylation in Arabidopsis antibacterial defense

A Yu, G Lepère, F Jay, J Wang… - Proceedings of the …, 2013 - National Acad Sciences
DNA demethylation restricts multiplication and vascular propagation of the bacterial …
regulated by DNA methylation. This study provides evidence that DNA demethylation is part of a …