Dynamic DNA methylation during aging: a “prophet” of age-related outcomes
FH Xiao, HT Wang, QP Kong - Frontiers in genetics, 2019 - frontiersin.org
… in patients with certain age-related diseases (eg, Alzheimer’s disease, cardiovascular disease).
… of the dynamic signatures of DNA methylation during aging and emphasize its practical …
… of the dynamic signatures of DNA methylation during aging and emphasize its practical …
Aging effects on DNA methylation modules in human brain and blood tissue
… Alzheimer's disease [29]. While DNA methylation is known to play a role in age-related
neurodegenerative diseases such as Alzheimer's disease [30, 31], our results indicate that a …
neurodegenerative diseases such as Alzheimer's disease [30, 31], our results indicate that a …
Mendelian randomization integrating GWAS and mQTL data identified novel pleiotropic DNA methylation loci for neuropathology of Alzheimer's disease
D Liu, Y Wang, H Jing, Q Meng, J Yang - Neurobiology of Aging, 2021 - Elsevier
… pathogenesis of Alzheimer's disease (… Aging Project, we undertook a Mendelian randomization
approach integrating genome-wide association studies (GWASs) and DNA methylation …
approach integrating genome-wide association studies (GWASs) and DNA methylation …
Association of blood-based DNA methylation markers with late-onset Alzheimer disease: a potential diagnostic approach
B Acha, J Corroza, J Sánchez-Ruiz de Gordoa… - Neurology, 2023 - AAN Enterprises
… etiology following the National Institute on Aging and Alzheimer's Association criteria
revised in 2011. Age-matched individuals (older than 65 years) with normal cognitive function …
revised in 2011. Age-matched individuals (older than 65 years) with normal cognitive function …
[HTML][HTML] Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer's disease
… Novel collection of multi-region brain 5′-cytosine DNA methylation data was performed for
the … DNA methylation signature of human hippocampus in Alzheimer's disease is linked to …
the … DNA methylation signature of human hippocampus in Alzheimer's disease is linked to …
The role for oxidative stress in aberrant DNA methylation in Alzheimer's disease
J L. Fleming, C J. Phiel… - Current Alzheimer …, 2012 - benthamdirect.com
… Is metabolic evidence for vitamin B-12 and folate deficiency more frequent in elderly patients
with Alzheimer's disease? J Gerontol A Biol Sci Med Sci 52: M76-9 (1997). [59] Agnati LF, …
with Alzheimer's disease? J Gerontol A Biol Sci Med Sci 52: M76-9 (1997). [59] Agnati LF, …
DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease
… microarray values (C) and pyrosequencing (D) in the frontal cortex of APP-PSEN1 and
3xTg-AD Alzheimer's disease mouse models in relation to their corresponding controls. …
3xTg-AD Alzheimer's disease mouse models in relation to their corresponding controls. …
Elevated DNA methylation across a 48‐kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology
… (Bristol Research into Alzheimer's and Care of the Elderly) to KL Brain banking and
neuropathology assessments for the discovery cohort from the Mount Sinai Alzheimer's disease and …
neuropathology assessments for the discovery cohort from the Mount Sinai Alzheimer's disease and …
[HTML][HTML] DNA methylation and cognitive aging
X Xu - Oncotarget, 2015 - ncbi.nlm.nih.gov
… more susceptible to neurodegenerative disorders such as Alzheimer's disease, whereas
granule … neuronal vulnerability in hippocampal aging and age-related disorders is unknown yet. …
granule … neuronal vulnerability in hippocampal aging and age-related disorders is unknown yet. …
Methylation differences in Alzheimer's disease neuropathologic change in the aged human brain
… In addition to novel ADNC related DNA methylation changes, … methylation differences
associated with Alzheimer's disease, … , NIA-AA National institute of Aging Alzheimer's Association …
associated with Alzheimer's disease, … , NIA-AA National institute of Aging Alzheimer's Association …