DNA methylation and cancer

M Kulis, M Esteller - Advances in genetics, 2010 - Elsevier
… tissue-specific DNA methylation in cancer (eg, BRCA1 is hypermethylated exclusively in
breast and ovarian carcinomas), the identification of different cancer types by DNA methylation

DNA methylation and cancer

PW Laird, R Jaenisch - Human molecular genetics, 1994 - academic.oup.com
… It is essential to our understanding of the role of DNA methylation in cancer to find out whether
the changes seen in DNA methylation patterns and MTase expression contribute to or are …

DNA methylation and cancer

PM Das, R Singal - Journal of clinical oncology, 2004 - ascopubs.org
… Because DNA methylation is reversible, drugs like 5′-azacytidine, … DNA methyl transferase
and small interference RNA are being developed, making the field of DNA methylation

DNA methylation and cancer

PA Jones - Oncogene, 2002 - nature.com
… 9 methylation is also necessary for some DNA methylation in … , suggesting ways in which
DNA methylation patterns may be … carcinogenesis where DNA methylation patterns become …

DNA methylation in cancer: too much, but also too little

M Ehrlich - Oncogene, 2002 - nature.com
… identifying cancer-specific differences in genome methylationDNA methylation that occur
upon cell culture (Smiraglia et al., 2001). In this review, only cancer-specific DNA methylation

Analysis of DNA methylation in cancer: location revisited

A Koch, SC Joosten, Z Feng, TC de Ruijter… - Nature reviews Clinical …, 2018 - nature.com
… genomic location of a DNA methylation-based biomarker is an … of DNA methylation for the
development of cancer biomarkers, … for the development of DNA methylation-based biomarkers …

The role of DNA methylation in cancer development.

MW Luczak, PP Jagodziński - Folia histochemica et …, 2006 - journals.viamedica.pl
… Carcinogenesis can also result from aberrations in genomic DNA methylation that include
hypermethylation and hypomethylation of promoter or first exon of cancer-related genes. …

DNA methylation and cancer

RL Momparler, V Bovenzi - Journal of cellular physiology, 2000 - Wiley Online Library
DNA suggesting that epigenetics plays an important role in tumorigenesis. The potent and
specific inhibitor of DNA methylation, … inhibitors of DNA methylation in patients with cancer and …

DNA methylation and cancer

PC Taberlay, PA Jones - Epigenetics and Disease: Pharmaceutical …, 2011 - Springer
… Silencing by DNA Methylation The biology of DNA methylation events in cancer is currently
DNA methylation is a relatively stable modification that occurs in the context of CpG …

DNA methylation in cancer and aging

M Klutstein, D Nejman, R Greenfield, H Cedar - Cancer research, 2016 - AACR
… tissues to cancer, and it is very likely that DNA methylation is … is characterized by changes in
DNA methylation very similar to … generation of abnormal DNA methylation patterns is oxygen …