Relationships between chromatin organization and DNA methylation in determining gene expression

PL Jones, AP Wolffe - Seminars in cancer biology, 1999 - Elsevier
… of DNA in the eukaryotic nucleus we can discuss the molecular mechanisms by which
DNA methylation influences the structure and function of chromatin and chromosomes. …

Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells

MC Lorincz, DR Dickerson, M Schmitt… - Nature structural & …, 2004 - nature.com
… As the methylated region adopts a closed chromatin structure in vivo, we propose that dense
intragenic DNA methylation in mammalian cells initiates formation of a chromatin structure …

Effect of DNA methylation and chromatin structure onITGAL expression

Q Lu, D Ray, D Gutsch… - Blood, The Journal of the …, 2002 - ashpublications.org
… asked if DNA methylation and/or chromatin structure could … Bisulfite sequencing was used
to compare methylation patterns in … methylated in fibroblasts but not T cells, and methylation

Cancer epigenetics: DNA methylation and chromatin alterations in human cancer

M Esteller - New Trends in Cancer for the 21st Century …, 2003 - Springer
Aberrations in the DNA methylation patterns are nowadays recognized as a hallmark of human
cancer One of the most characteristic changes is the hypermethylation of CpG islands of …

[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics

S Li, Y Peng, AR Panchenko - Current opinion in structural biology, 2022 - Elsevier
… structure include using murine DNA methyltransferases in budding yeast which … lack DNA
methylation machinery [8∗∗]. This approach found that DNA methylation resulted in chromatin

Joint profiling of DNA methylation and chromatin architecture in single cells

G Li, Y Liu, Y Zhang, N Kubo, M Yu, R Fang, M Kellis… - Nature …, 2019 - nature.com
chromatin states (Supplementary Fig. 4). … chromatin conformation and DNA methylation
together in single cells. Cellular heterogeneity presents a significant challenge for chromatin

DNA methylation and chromatin modifiers in colorectal cancer

V Vymetalkova, P Vodicka, S Vodenkova… - Molecular aspects of …, 2019 - Elsevier
… , or phosphorylation determine the accessibility of transcription factors to DNA. DNA
methylation, a chemical modification of DNA that modulates chromatin structure and gene …

DNA methylation and chromatin structure regulate T cell perforin gene expression

Q Lu, A Wu, D Ray, C Deng, J Attwood… - The Journal of …, 2003 - journals.aai.org
… We observed that DNA methylation inhibition could increase perforin expression in T cells,
so we examined the methylation pattern and chromatin structure of the human perforin …

DNA damage and repair modify DNA methylation and chromatin domain of the targeted locus: mechanism of allele methylation polymorphism

G Russo, R Landi, A Pezone, A Morano… - Scientific Reports, 2016 - nature.com
DNA repair (HR). We find that HR modifies the DNA methylation pattern of the repaired
segment… HR also alters local histone H3 methylation as well chromatin structure by inducing DNA-…

DNA methylation-linked chromatin accessibility affects genomic architecture in Arabidopsis

Z Zhong, S Feng, SH Duttke… - Proceedings of the …, 2021 - National Acad Sciences
DNA methylation and chromatin accessibility, we performed assay for transposase-accessible
chromatin … show that chromatin accessibility anticorrelates with DNA methylation, as has …