Defining driver DNA methylation changes in human cancer

GP Pfeifer - International journal of molecular sciences, 2018 - mdpi.com
… clear how these DNA methylation changes are initiated. … DNA methylation changes are
truly tumor-driving events. Although changes in DNA methylation, in the form of both overall DNA

Rapid DNA methylation changes after exposure to traffic particles

A Baccarelli, RO Wright, V Bollati… - American journal of …, 2009 - atsjournals.org
… global genomic DNA methylation content (1, 5). Although changes in DNA methylation have
… Epidemiologic time-series studies have identified an association between daily changes in …

DNA methylation changes in leukaemia

JR Melki, SJ Clark - Seminars in cancer biology, 2002 - Elsevier
… This review will discuss the multitude of DNA methylation changes in … methylation, and
further showed regions displaying hypermethylation. This paper reviews the epigenetic changes

DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies

X Gao, M Jia, Y Zhang, LP Breitling, H Brenner - Clinical epigenetics, 2015 - Springer
… In conclusion, this review summarizes the evidences for the use of blood DNA methylation
patterns as biomarkers of smoking exposure for research and clinical practice. In particular, it …

[PDF][PDF] Epigenomic profiling reveals DNA-methylation changes associated with major psychosis

J Mill, T Tang, Z Kaminsky, T Khare… - The American Journal of …, 2008 - cell.com
… a strong correlation between DNA methylation in the MEK1 … Finally, we observe that
frontal-cortex DNA methylation in the … and suggest that DNA-methylation changes are important to …

DNA methylation and healthy human aging

MJ Jones, SJ Goodman, MS Kobor - Aging cell, 2015 - Wiley Online Library
… Both epigenetic drift and the epigenetic clock contribute to age-related DNA methylation
changes, … Here, we define epigenetic drift as the collection of DNA methylation changes that are …

Understanding the relevance of DNA methylation changes in immune differentiation and disease

C Calle-Fabregat, O Morante-Palacios, E Ballestar - Genes, 2020 - mdpi.com
DNA methylation in health and disease. This review considers the relevance of DNA methylation
… as well as the participation of DNA methylation defects in immune-mediated pathologies…

DNA methylation changes in multiple myeloma

O Galm, S Wilop, J Reichelt, E Jost, G Gehbauer… - Leukemia, 2004 - nature.com
Using a candidate gene approach, we analyzed the methylation status of the promoter-associated
CpG islands of 11 well-characterized tumor suppressor genes by methylation-specific …

DNA methylation changes in ovarian cancer: implications for early diagnosis, prognosis and treatment

CA Barton, NF Hacker, SJ Clark, PM O'Brien - Gynecologic oncology, 2008 - Elsevier
… be detected in DNA circulating in … changes has promise in molecular classification and
disease stratification. CONCLUSIONS: The detection of cancer-specific DNA methylation changes

Age-dependent DNA methylation changes in the ITGAL (CD11a) promoter

Z Zhang, C Deng, Q Lu, B Richardson - Mechanisms of ageing and …, 2002 - Elsevier
… This suggests that some of the functional changes associated with … DNA methylation patterns.
To further define the role that altered DNA methylation plays in age-associated changes in …