DNA methylation dynamics of the human preimplantation embryo

ZD Smith, MM Chan, KC Humm, R Karnik… - Nature, 2014 - nature.com
… extent to which early embryonic landscapes are conserved 8,9,10 . We present genome-scale
DNA methylation maps of human preimplantation development and embryonic stem cell …

DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
… However, DNA methylation marks must be globally removed to allow for sexual … the
preimplantation embryo. Recent technological advances in genome-wide DNA methylation analysis …

Dynamic regulation of DNA methyltransferases in human oocytes and preimplantation embryos after assisted reproductive technologies

L Petrussa, H Van de Velde… - Molecular human …, 2014 - academic.oup.com
… As DNA methylation dynamics are not well conserved in mammals (Ikeda et al., 2010; Ma
et al., 2012), the primary goal of this study was to investigate the spatial and temporal …

Genome-wide analysis of DNA methylation dynamics during early human development

H Okae, H Chiba, H Hiura, H Hamada, A Sato… - PLoS …, 2014 - journals.plos.org
… CGIs could regulate mono-allelic expression of some genes in human preimplantation
embryos. In the mouse genome, ∼25 well defined gDMRs have been identified and only the …

Dynamics of DNA methylation during early development of the preimplantation bovine embryo

KB Dobbs, M Rodriguez, MJ Sudano, MS Ortega… - PloS one, 2013 - journals.plos.org
There is species divergence in control of DNA methylation during preimplantation development.
The exact pattern of methylation in the bovine embryo has not been established nor has …

Evaluation of genome-wide DNA methylation profile of human embryos with different developmental competences

M Yang, X Tao, K Scott, Y Zhan, RT Scott Jr… - Human …, 2021 - academic.oup.com
DNA methylation is a … pre-implantation embryo development. Currently there is no established
approach available to assess the epigenetic status of the human preimplantation embryo

Reprogramming of DNA methylation is linked to successful human preimplantation development

J Arand, RA Reijo Pera, M Wossidlo - Histochemistry and Cell Biology, 2021 - Springer
… of DNA methylation (5mC) in early human preimplantation development to gain further
insights into epigenetic reprogramming of human embryos. … preimplantation embryos to further …

Expression dynamics of repetitive DNA in early human embryonic development

C Yandım, G Karakülah - BMC genomics, 2019 - Springer
DNA-methylation levels of all repeats utilising another published dataset on single cells of
human pre-implantation embryos [… DNA methylation dynamics of major repeat classes during …

DNA methylation dynamics in mouse preimplantation embryos revealed by mass spectrometry

Y Okamoto, N Yoshida, T Suzuki, N Shimozawa… - Scientific reports, 2016 - nature.com
… Because embryo culture has been reported to affect DNA methylation 38 , we determined
5 mC profiles during preimplantation development following in vitro fertilization (IVF). We also …

A DNA methylation state transition model reveals the programmed epigenetic heterogeneity in human pre-implantation embryos

C Zhao, N Zhang, Y Zhang, N Tuersunjiang, S Gao… - Genome Biology, 2020 - Springer
… -modifying activities in order to link the methylation states before and after a … DNA methylome
data from human pre-implantation embryogenesis and elucidate that the DNA methylation