… (B) DNA methylation writing, maintenance and erasure involves … (C) DNA methylation erasure
occurs through active or … out by DNA synthesis without maintenance methylation, leading …

… methylation on a large portion of the genome in developing male and female PGCs isolated
from mouse embryos. We show that DNA methylation erasure … global methylation erasure in …

… with aberrant sperm DNA methylation may provide long-awaited mechanistic insights into
abnormal sperm function. If, as we now postulate, improper erasure of DNA methylation in …

… and regulation of DNA methyltransferases in … erasure of DNA methylation patterns are not
yet fully elucidated, and the exact molecular mechanisms leading to the aberrant methylation …

… sperm epimutations appear to escape DNA methylation erasure to impact embryonic cell …
found to escape DNA methylation erasure and generally have an increase in DNA methylation. …

… recruits a DNA methylation eraser, TET3, to catalyse DNA demethylation at the … DNA
methylation through cooperative action of the transcription factor C/EBPδ, and the DNA methylation …

… Our results reveal that erasure of DNA methylation in the germ line is a global process, …
AID deficiency interferes with genome-wide erasure of DNA methylation patterns, indicating that …

… L1HS retrotransposons have similar DNA methylation levels to D4 hPGCLCs… DNA methylation
relative to D4 hPGCLCs (Figures S5H and S5I). Protein coding genes also exhibited DNA …

… in erasure of DNA methylation in primordial germ cells ( 12 ). It is noteworthy that AID
promotes 5mC deamination, resulting in thymine ( 10 , 13 ), as well as 5hmC deamination, which …

… We show genome-wide dynamics of 5meC and 5hmeC erasure during PSC … DNA methylome,
including previously known and unknown gDNA elements resistant to the global erasure …