Erasure of cellular memory by fusion with pluripotent cells

JT Do, DW Han, L Gentile, I Sobek-Klocke… - Stem Cells, 2007 - academic.oup.com
… of gene expression change along with alterations of DNA methylation. In our current study,
we … Specifically, we examined the change of gene expression and DNA methylation of fusion …

Incomplete erasure of histone marks during epigenetic reprogramming in medaka early development

HS Fukushima, H Takeda, R Nakamura - Genome Research, 2023 - genome.cshlp.org
… In mice, DNA methylation and histone modifications transmitted from parental germ cells are
globally reset in early embryos. However, some modifications are known to persist and play …

Erasure and reestablishment of random allelic expression imbalance after epigenetic reprogramming

AR Jeffries, DA Uwanogho, G Cocks, LW Perfect… - Rna, 2016 - rnajournal.cshlp.org
… 2A,B) show only modest changes associated with developmental state, although we
observe large changes in DNA methylation at specific CpG sites; 40,425 CpGs of 415,863 were …

DNA methylation reprogramming in the germ line

DJ Lees-Murdock, CP Walsh - Epigenetics, 2008 - Taylor & Francis
… Following erasure of imprints and partial erasure of methylation on repeats, these … seen
in the germ cells make sense given what we know or suspect about DNA methylation? On the …

DNA methylation: basic principles

CA Moylan, SK Murphy - Medical Epigenetics, 2016 - Elsevier
… This chapter provides an introduction to DNA methylation and will cover the nature of DNA
methylation, how it … By erasing DNA methylation that exists on the parental chromosomes, any …

Roles, and establishment, maintenance and erasing of the epigenetic cytosine methylation marks in plants

S Kumar, R Kumari, V Sharma, V Sharma - Journal of genetics, 2013 - Springer
… The variation in DNA methylation patterns arises because not all of the putative … of DNA
methylation among different classes of eukaryotes. Transposons and repeats are methylated in …

Epigenetic erasure in ectopic primordial germ cells

S Fang - 2024 - open.library.ubc.ca
… this study, we explore the developmental mechanism of methylation erasure within PGCs …
To do so, we examine hallmarks of DNA methylation erasure in ectopic PGCs—germ cells …

[HTML][HTML] The Arabidopsis active demethylase ROS1 cis-regulates defence genes by erasing DNA methylation at promoter-regulatory regions

T Halter, J Wang, D Amesefe, E Lastrucci, M Charvin… - Elife, 2021 - elifesciences.org
DNA methylation is an epigenetic mark that negatively … Homeostasis of DNA methylation
relies on the equilibrium … a major role for DNA methylation in susceptibility against non-…

Regulation of DNA methylation turnover at LTR retrotransposons and imprinted loci by the histone methyltransferase Setdb1

D Leung, T Du, U Wagner, W Xie… - Proceedings of the …, 2014 - National Acad Sciences
… Here, we report that a subset of such genomic regions are resistant to widespread
erasure of DNA methylation in mouse embryonic stem cells (mESCs) lacking the de novo …

DNA methylation dynamics during the mammalian life cycle

JA Hackett, MA Surani - … of the Royal Society B: Biological …, 2013 - royalsocietypublishing.org
… Conversion to 5-hydroxymethylcytosine (5hmC) by TET proteins is likely a hub for
demethylation (central box) and can lead to either passive or active erasure of DNA methylation. …