DNA methylation in health and disease
KD Robertson, AP Wolffe - Nature reviews genetics, 2000 - nature.com
… In this article, we first summarize the basics of DNA methylation in the genome and … methylation
machinery and its role in development. We also discuss the functions of DNA methylation …
machinery and its role in development. We also discuss the functions of DNA methylation …
DNA methylation in health, disease, and cancer
DS Shames, JD Minna… - Current molecular …, 2007 - ingentaconnect.com
… The major focus of this review involves DNA methylation and its role in cancer development.
However, the influence of histones and their modifications, as well as the PcgTrxG proteins …
However, the influence of histones and their modifications, as well as the PcgTrxG proteins …
DNA methylation, early life environment, and health outcomes
C Mitchell, LM Schneper, DA Notterman - Pediatric research, 2016 - nature.com
… environment can affect health. Strong evidence … health, wellbeing, and behavior (2,3,4).
This review describes some of the recent work in this area, but first reviews DNA methylation (its …
This review describes some of the recent work in this area, but first reviews DNA methylation (its …
DNA methylation dynamics in health and disease
Y Bergman, H Cedar - Nature structural & molecular biology, 2013 - nature.com
… DNA methylation is an epigenetic mark that is erased in the early embryo and then re-established
at the time of implantation. In this Review, dynamics of DNA methylation … methylation …
at the time of implantation. In this Review, dynamics of DNA methylation … methylation …
DNA methylation 40 years later: Its role in human health and disease
MI Scarano, M Strazzullo, MR Matarazzo… - Journal of cellular …, 2005 - Wiley Online Library
… Here, we review the impact of the studies on DNA methylation, the “primadonna” in the …
The effect of deregulation of DNA methylation on human health, will be also discussed. …
The effect of deregulation of DNA methylation on human health, will be also discussed. …
DNA methylation and regulation of gene expression: Guardian of our health
GA Dhar, S Saha, P Mitra, R Nag Chaudhuri - The Nucleus, 2021 - Springer
… As discussed earlier, DNA methylation is a critical parameter affecting our health and well-being.
The current review primarily aims to bring a holistic picture of the crosstalk between …
The current review primarily aims to bring a holistic picture of the crosstalk between …
Insufficient DNA methylation affects healthy aging and promotes age-related health problems
… and other health conditions during the aging process. Our results clearly support the likelihood
that insufficient DNA methylation can lead to early onset of sub-optimal health conditions …
that insufficient DNA methylation can lead to early onset of sub-optimal health conditions …
A systematic review and meta-analysis of environmental, lifestyle, and health factors associated with DNA methylation age
J Ryan, J Wrigglesworth, J Loong… - The Journals of …, 2020 - academic.oup.com
DNA methylation (DNAm) algorithms of biological age provide a robust estimate of an
individual’s chronological age and can predict their risk of age-related disease and mortality. This …
individual’s chronological age and can predict their risk of age-related disease and mortality. This …
DNA methylation-based predictors of health: applications and statistical considerations
… to the development of DNA methylation-based predictors across a wide range of health-related …
This Review evaluates the progress of existing DNA methylation-based predictors, …
This Review evaluates the progress of existing DNA methylation-based predictors, …
Impact of DNA methylation on health and disease
M Esteller - DNA Methylation: Approaches, Methods, and …, 2005 - books.google.com
… Chapter 3 reflects the relevance of DNA methylation to the control of gene imprinting and
X inactivation. In summary, the disruption of DNA methylation patterns is a major hallmark of …
X inactivation. In summary, the disruption of DNA methylation patterns is a major hallmark of …
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