The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… of DNA methylation and its establishment, maintenance and erasure during mammalian
development. … gained into the patterning of DNA methylation during development. Finally, we …

Expression of various genes is controlled by DNA methylation during mammalian development

M Ehrlich - Journal of cellular biochemistry, 2003 - Wiley Online Library
DNA methylation controlling their expression during normal mammalian development and
a … For descriptions of some of the evidence for DNA methylation-controlled expression of X-…

Notes on the role of dynamic DNA methylation in mammalian development

TH Bestor, JR Edwards… - Proceedings of the …, 2015 - National Acad Sciences
… a major role for DNA methylation in mammalian development, as do the low levels of
promoter methylation and lack of ectopic gene activation after reduction or removal of genomic …

DNA methylation: roles in mammalian development

ZD Smith, A Meissner - Nature Reviews Genetics, 2013 - nature.com
… two developmental periods, primordial germ cell (PGC) specification and the early embryo,
in which DNA methylation … principles of DNA methylation in mammalian development and set …

The role of DNA methylation in mammalian development

CE Senner - Reproductive biomedicine online, 2011 - Elsevier
… This review considers the dynamic patterns of DNA methylation throughout gametogenesis,
preimplantation development and early lineage commitment, along with recent insights into …

DNA methylation in mammalian development and disease

W Dean, D Lucifero, F Santos - Birth Defects Research Part C …, 2005 - Wiley Online Library
… Establishing the importance of DNA methylation and its regulation to ensure normal
mammalian development naturally forces us to consider the possibilities and repercussions of its …

Dynamic regulation of DNA methylation during mammalian development

S Guibert, T Forné, M Weber - Epigenomics, 2009 - Taylor & Francis
… showed that DNA methylation is targeted to important developmental genes … DNA methylation
in mammalian genomes, with particular emphasis on the waves of global DNA methylation

Functions of DNA methylation and hydroxymethylation in mammalian development

S Guibert, M Weber - Current topics in developmental biology, 2013 - Elsevier
DNA methylation plays multiple roles during development and serves to establish long-term
gene … discoveries on the role of cytosine epigenetic marks during mammalian development. …

DNA methylation reprogramming during mammalian development

Y Zeng, T Chen - Genes, 2019 - mdpi.com
… , are usually devoid of methylation [2]. DNA methylation is essential for mammalian development
and is involved in … Aberrant DNA methylation patterns and mutations of genes encoding …

DNA methylation in mammals

E Li, Y Zhang - Cold Spring Harbor perspectives in …, 2014 - cshperspectives.cshlp.org
development new DNA methylation patterns are established in an individual and how de
novo methylation … and methylation patterns of CpG sequences in the mammalian genome and …