… and for aberrant DNA in cancer. To determine the feasibility of DNA methylation studies in
… samples or among the different pathological entities in any region analyzed. Because small …

… protein precursor post-translational processing, supporting a role for epigenetic change in
LOAD pathology. This study demonstrates widespread, modest discordant DNA methylation in …

… We performed a genome-wide screen of DNA methylation … temporal gyrus of patients with
Alzheimer’s disease and non-… to the influence of DNA methylation in AD pathogenesis [15], …

… In stage 1, we carried out a DNA methylation screen for chromosomal regions in which
methylation levels correlate with AD pathology (Online Methods). In stage 2, we replicated the …

… DNAm associated with cerebrospinal fluid (CSF) pathological biomarkers for AD. Our study
included matched samples of whole blood DNA methylation, CSF Aβ 42 , phosphorylated tau …

… Together, these strategies enabled us to identify a list of informative and unbiased regulatory
changes in DNA methylation associated with AD pathology. Remarkably, we found a …

… is evidence suggesting an involvement of environmental factors in the pathogenesis of
Alzheimer's disease (AD), which prompted our study examining DNA methylation in this disorder. …

… Alzheimer's disease pathology and reduced cognitive performance. In this study, we present
the largest study of DNA methylation… and environmental Alzheimer's disease risk factors in a …

… association studies (MWAS) in humans have solidified the concept that aberrant DNA
methylation is associated with Alzheimer's disease (… also show AD pathology [134]. However, this …

… DNA methylation changes of noncoding RNA genes in the temporal cortex samples from
individuals with Alzheimer’s disease (AD… to the pathogenesis of Alzheimer’s disease (AD) [1, 2]. …