… The two waves of DNA methylation reprogramming involve both distinct and shared … the
key reprogramming events, focusing on the important players in these processes, including DNA …

… emphasis on DNA methylation during cellular reprogramming. Recent data suggest that
DNA methylation is a major barrier to induced pluripotent stem (iPS) cell reprogramming. The …

… Reprogramming methylation in the primordial germ cells … In addition to direct transcriptional
silencing, DNA methylation … and extent of DNA methylation reprogramming of many different …

… De novo methylation was observed specifically in the inner cell mass (ICM) … reprogramming
cycle during preimplantation development. The three phases of methylation reprogramming …

… Cells transduced with ZF-97 SKD did not exhibit targeted DNA methylation (Fig. S1). To
determine if we could directionally target DNA methylation, we positioned the DNMT3a domain …

… methylation erasure from the zygote. Deamination by AID, BER and passive demethylation
have been implicated in reprogramming … the dynamics of DNA methylation reprogramming in …

… Consistent with these reports, we did not observe widespread changes of DNA methylation
during reprogramming in the CpG islands on chromosomes 12 and 20. Surprisingly, we still …

… Reprogramming of somatic cells to induced pluripotent stem cells involves a … reprogramming
as part of Project Grandiose. We find that DNA methylation gain during reprogramming …

… Genome-wide DNA methylation reprogramming occurs in mouse primordial germ cells (PGCs)
and preimplantation embryos, but the precise dynamics and biological outcomes are …

… of DNA methylation inheritance through semiconservative DNA replication, which implied
two … modes of DNA methylation activity: maintenance methylation and de novo methylation (…