DNA methylation reprogramming during mammalian development

Y Zeng, T Chen - Genes, 2019 - mdpi.com
… However, the epigenome, including DNA methylation, needs to be reprogrammed to a …
embryogenesis [6,7]. Epigenetic reprogramming in the germline involves the erasure of somatic …

DNA methylation reprogramming of functional elements during mammalian embryonic development

C Li, Y Fan, G Li, X Xu, J Duan, R Li, X Kang, X Ma… - Cell discovery, 2018 - nature.com
… We further show that methylation reprogramming of enhancers during early embryogenesis
is highly … Our data support the hypothesis that DNA methylation plays important roles during …

[HTML][HTML] Conceptual links between DNA methylation reprogramming in the early embryo and primordial germ cells

S Seisenberger, JR Peat, W Reik - Current opinion in cell biology, 2013 - Elsevier
… demethylation dynamics during epigenetic reprogramming. In addition, … DNA methylation
erasure in the early embryo and PGCs, further adding to our mechanistic understanding of DNA

DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

DM Messerschmidt, BB Knowles… - Genes & …, 2014 - genesdev.cshlp.org
… the preimplantation embryo. Recent technological advances in genome-wide DNA methylation
analysis and the functional description of novel enzymatic DNA demethylation pathways …

Dynamic reprogramming of DNA methylation in the early mouse embryo

F Santos, B Hendrich, W Reik, W Dean - Developmental biology, 2002 - Elsevier
… This is the first complete and detailed analysis of the epigenetic reprogramming cycle during
preimplantation development. The three phases of methylation reprogramming may have …

Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo

J Arand, M Wossidlo, K Lepikhov, JR Peat, W Reik… - Epigenetics & …, 2015 - Springer
… between possible mechanisms of DNA methylation reprogramming (that is, demethylation
and de novo methylation) and DNA methylation maintenance in the early mouse embryo. …

Germline-derived DNA methylation and early embryo epigenetic reprogramming: the selected survival of imprints

D Monk - The international journal of biochemistry & cell biology, 2015 - Elsevier
… and trans-generation inheritance, since the methylation patterns must first be … embryo and
survive the wave of reprogramming to occurs during pre-implantation embryonic development. …

Effect of limited DNA methylation reprogramming in the normal sheep embryo on somatic cell nuclear transfer

N Beaujean, J Taylor, J Gardner, I Wilmut… - Biology of …, 2004 - academic.oup.com
… limited methylation reprogramming in the normal sheep embryo on reprogramming somatic
… and undergo a stepwise passive loss of DNA methylation during early development, as …

DNA methylation dynamics and MET1a-like gene expression changes during stress-induced pollen reprogramming to embryogenesis

MT Solís, M Rodríguez-Serrano… - Journal of …, 2012 - academic.oup.com
reprogramming after microspore embryogenesis induction which involved a decrease of global
DNA methylation … proliferation, while DNA methylation increases with pollen and embryo

Placeholder nucleosomes underlie germline-to-embryo DNA methylation reprogramming

PJ Murphy, SF Wu, CR James, CL Wike, BR Cairns - Cell, 2018 - cell.com
… to-embryo epigenetics: how are paternal DNA methylation patterns maintained and maternal
DNA methylation patterns reprogrammed … in programming in vivo DNA methylation patterns …