[HTML][HTML] Increased DNA methylation variability in type 1 diabetes across three immune effector cell types

DS Paul, AE Teschendorff, MAN Dang, R Lowe… - Nature …, 2016 - nature.com
… Second, we propose the complementary assessment of DNA methylation variability in parallel
to mean DNA methylation for any future EWAS. Analytical tools are now readily available …

DNA methylation contributes to natural human variation

H Heyn, S Moran, I Hernando-Herraez… - Genome …, 2013 - genome.cshlp.org
… However, the causal chain of events establishing DNA methylation variability, which is
currently under debate, is likely to be mediated in a network of genomic contexts, transcriptional …

Differential variability improves the identification of cancer risk markers in DNA methylation studies profiling precursor cancer lesions

AE Teschendorff, M Widschwendter - Bioinformatics, 2012 - academic.oup.com
… In this manuscript we formally demonstrate, in the context of DNA methylation studies …
variability identifies true positives more reliably than statistics based on differential methylation. We …

Implementing a method for studying longitudinal DNA methylation variability in association with age

Y Wang, NL Pedersen, S Hägg - Epigenetics, 2018 - Taylor & Francis
… in methylation variability in association with age. However, thus far, no method explored DNA
methylation variability in … methods for estimating methylation variability in longitudinal data. …

Genome-wide DNA methylation variability in adolescent monozygotic twins followed since birth

ML Lévesque, KF Casey, M Szyf, E Ismaylova, V Ly… - Epigenetics, 2014 - Taylor & Francis
… Here, we assessed genome-wide DNA methylation using the … : 1) the extent of variation in
DNA methylation in identical genetic … We also assessed stability of DNA methylation over 3–6 …

Evaluating DNA methylation and gene expression variability in the human term placenta

L Avila, RK Yuen, D Diego-Alvarez, MS Penaherrera… - Placenta, 2010 - Elsevier
DNA methylation variability in the placenta, sites that exhibit inter-placental variability need
… The promoter region of KISS1 was found to exhibit an intermediate and variable methylation

DNA methylation variability in Alzheimer's disease

Z Huo, Y Zhu, L Yu, J Yang, P De Jager, DA Bennett… - Neurobiology of …, 2019 - Elsevier
… , we found that the variability in DNA methylation was related to AD … DNA methylation
variability in AD pathology and highlight the importance of testing DNA methylation variability

Epigenetic variability in systemic lupus erythematosus: what we learned from genome-wide DNA methylation studies

M Teruel, AH Sawalha - Current rheumatology reports, 2017 - Springer
DNA methylation has emerged as an important contributing factor in the pathogenesis of
systemic lupus erythematosus (SLE). Here, we describe the DNA methylation patterns identified …

Extensive variation and low heritability of DNA methylation identified in a twin study

K Gervin, M Hammerø, HE Akselsen, R Moe… - Genome …, 2011 - genome.cshlp.org
DNA methylation in a large set of healthy MZ and DZ twins to investigate inter-individual
variation, patterns of DNA methylation, … far less to the overall methylation variability than do the …

Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes

N Chambwe, M Kormaksson, H Geng… - Blood, The Journal …, 2014 - ashpublications.org
… stochastic variation in DNA methylation across solid cancers … variability in DNA methylation
in DLBCL. Building on these prior observations, we sought to investigate if DNA methylation