… ; (c) attempts to modulate the metabolism of the cytotoxic drug; and (d) attempts to prevent
in… of drugs as prophylactic agents against chemotherapy- and radiation-induced oral mucositis…

… the use of oral cryotherapy to prevent oral mucositis and three studies analysed the …
Drugs that affect DNA synthesis, namely antimetabolites (methotrexate, 5-fluorouracil [5-FU]…

… The mechanism of action from this drug includes the cell … 1 (palifermin) for the prevention
of oral mucositis in patients with … As prophylaxis in Oral Mucositis is concerned in HSCT, …

… of different chemotherapeutic drugs further intensifies the likelihood of mucositis: from 40% …
There has been a range of interventions developed for prophylaxis of oral mucositis (Table 4) …

… to reduce or prevent mucositis while practices which have no … prevention and treatment of
oral mucositis will be based on a … chemotherapy-induced oral mucositis. Numerous agents and …

… Since infection may have an important role in the pathophysiology of oral mucositis, several
… assessment of oral mucositis made comparison of outcomes difficult. Newer drugs, such as …

… Similar results were also reported in 30 patients randomized to receive prophylactic helium-…
) also were improved in patients who received prophylactic helium-neon laser radiotherapy. …

… Importantly for drug developers, the biology of oral mucositis is … Thus, an agent that is
efficacious for oral mucositis should … -party payers when prophylactic administration is required for …

… Oral mucositis prevalence was lower and it appeared significantly later in patients treated
with prophylactic … drug locally in the oral cavity, did not reduce the severity and duration of …

… by the United States food and drug administration (US-FDA) to … infections, nutritional support,
and prophylaxis are regarded as the … Proper prophylaxis and management may prevent the …