Effect of gefitinib combined with chemotherapy in patients with advanced NSCLC: A retrospective cohort study

L Dai, W Wang, W Li, Y Wu, K Qu - International Journal of General …, 2022 - Taylor & Francis
… NEJ009 study is the first randomized Phase III trial that compared gefitinib plus chemotherapy
with gefitinib in patients with … This study compared the efficacy of chemotherapy alone and …

Effect of gefitinib on the survival of patients with recurrence of lung adenocarcinoma after surgery: a retrospective case-matching cohort study

T Katayama, K Matsuo, T Kosaka, T Sueda, Y Yatabe… - Surgical Oncology, 2010 - Elsevier
… In this study, we assessed whether gefitinib improved the survival of adenocarcinoma patients
… We also examined whether the benefit of gefitinib, when present, was limited to a certain …

… Versus Adjuvant Chemotherapy in Patients with Stage II-IIIA Non–Small-Cell Lung Cancer Harboring Positive EGFR Mutations: A Single-Center Retrospective Study

H Xie, H Wang, L Xu, M Li, Y Peng, X Cai, Z Feng… - Clinical Lung Cancer, 2018 - Elsevier
… However, scarce evidence showing the superiority of gefitinib … a retrospective study to assess
the efficacy of adjuvant gefitinibGefitinib was associated with fewer grade 3/4 toxic effects

Comparing the effectiveness of different EGFR‐TKIs in patients with EGFR mutant non–small‐cell lung cancer: a retrospective cohort study in Taiwan

YY Hsieh, WT Fang, YW Lo, YH Chen… - International journal of …, 2020 - Wiley Online Library
… This retrospective cohort study was conducted using data from real-world settings. Patients
with stage IIIB and IV NSCLC and first received gefitinib, erlotinib, or afatinib between 2011 …

Gefitinib or erlotinib in previously treated non–small‐cell lung cancer patients: a cohort study in Taiwan

CH Chang, CH Lee, JC Ko, LY Chang… - Cancer …, 2017 - Wiley Online Library
… large retrospective cohort study used NHIRD to compare the outcome of two first-generation
EGFR-TKIs, erlotinib and gefitinib… Thus, gefitinib could achieve the maximal anticancer effect

Feasibility and effectiveness of afatinib for poor performance status patients with EGFR-mutation-positive non-small-cell lung cancer: a retrospective cohort study

CE Wu, CF Chang, CY Huang, CT Yang, CHS Kuo… - BMC cancer, 2021 - Springer
… A large cohort study based on the Taiwan Cancer Registry, conducted in 2011–2015,
compared the efficacy of three different TKIs—gefitinib, erlotinib, and afatinin. The results showed …

A retrospective analysis of 335 Japanese lung cancer patients who responded to initial gefitinib treatment

K Nishino, F Imamura, S Morita, M Mori, K Komuta… - Lung cancer, 2013 - Elsevier
… survival in an unbalanced retrospective cohort study. To solve this … retrospective study,
although it was performed based on a protocol. Third, it is difficult to analyze the effects of gefitinib

Comparison of effectiveness and adverse effects of gefitinib, erlotinib and icotinib among patients with non‑small cell lung cancer: A network meta‑analysis

Y Liu, Y Zhang, G Feng, Q Niu… - Experimental and …, 2017 - spandidos-publications.com
… According to the PICO principle, the following eligibility criteria were established: i) Research
includes a randomized controlled trial, case-control study or cohort study; ii) subjects are …

Nationwide real-world cohort study of first-line tyrosine kinase inhibitor treatment in epidermal growth factor receptor-mutated non–small-cell lung cancer

RGP Gijtenbeek, RAM Damhuis, HJM Groen… - Clinical lung cancer, 2020 - Elsevier
cohort. In patients with brain metastasis, erlotinib showed superior results compared with
gefitinib … The favorable effect of osimertinib might have been attenuated if more patients would …

Retrospective Analysis of Different Treatment Schemes After Gefitinib Resistance in Advanced Non–small Cell Lung Cancer

H Wang, M Zhang, P Li, G Zhang, X Yan, Z Ma - Clinical therapeutics, 2017 - Elsevier
gefitinib administration seems to be a reasonable choice for the treatment of local progression
or metastasis in such patients if these results are validated in future, larger cohort studies