Long-term safety and efficacy of indacaterol, a long-acting β2-agonist, in subjects with COPD: a randomized, placebo-controlled study

KR Chapman, SI Rennard, A Dogra, R Owen… - Chest, 2011 - Elsevier
… -term safety of indacaterol from a study … indacaterol, 150 or 300 μg, or placebo once daily
for a further 26 weeks. The primary objective was to evaluate the 52-week safety of indacaterol; …

Safety, tolerability and efficacy of indacaterol, a novel once-daily β2-agonist, in patients with COPD: a 28-day randomised, placebo controlled clinical trial

J Beier, P Chanez, JB Martinot, AJM Schreurs… - Pulmonary …, 2007 - Elsevier
… demonstrates that the novel once-daily β 2 -agonist indacaterol is well tolerated at doses up
… support the previously demonstrated 24-h bronchodilator efficacy of once-daily indacaterol. …

Bronchodilator efficacy of indacaterol, a novel once-daily β2-agonist, in patients with persistent asthma

DS Pearlman, L Greos, C LaForce, CJ Orevillo… - Annals of Allergy …, 2008 - Elsevier
… to investigate the 24-hour profile of bronchodilator efficacy of single doses of indacaterol,
400 μg, via single-dose dry powder inhaler (SDDPI) and indacaterol, 200 μg, via multidose dry …

Efficacy of a new once-daily long-acting inhaled β2-agonist indacaterol versus twice-daily formoterol in COPD

R Dahl, KF Chung, R Buhl, H Magnussen, V Nonikov… - Thorax, 2010 - thorax.bmj.com
… , indacaterol provided 24 h bronchodilation on once-daily dosing with a fast onset of action.
This study compared the efficacy and safety of indacaterol … was that indacaterol would have a …

Indacaterol, a once‐daily beta2agonist, versus twice‐daily beta2agonists or placebo for chronic obstructive pulmonary disease

JB Geake, EJ Dabscheck… - Cochrane Database …, 2015 - cochranelibrary.com
… To compare the efficacy and safety of indacaterol versus placebo and alternative twice‐daily
long‐acting beta 2agonists for the treatment of patients with stable COPD. …

Efficacy and Safety of Indacaterol, a New 24-hour β 2-Agonist, in Patients with Asthma: A Dose-Ranging Study

F Kanniess, LP Boulet, W Pierzchala… - Journal of …, 2008 - Taylor & Francis
… demonstrated that single doses of indacaterol provide 24-hour … When administered once
daily for 28 days, indacaterol is … the efficacy and safety of multiple doses of indacaterol (100, 200…

Efficacy of indacaterol in the treatment of patients with COPD

PW Jones, N Barnes, C Vogelmeier… - Primary Care …, 2011 - nature.com
… A oncedaily β2-agonist bronchodilator, indacaterol, was … evaluation of the efficacy and
safety of indacaterol and include … The objective of this paper is to review the efficacy of this new …

Comparative efficacy of indacaterol in chronic obstructive pulmonary disease

M Ribeiro, KR Chapman - International Journal of Chronic …, 2012 - Taylor & Francis
… In vitro studies during the preclinical development of indacaterol Citation13 characterized
this new agent as having high agonist efficacy at the human β2-adrenoreceptor, with a binding …

Indacaterol, a novel inhaled, once-daily, long-acting beta2-agonist for the treatment of obstructive airways diseases

KM Beeh, J Beier - Advances in therapy, 2009 - Springer
Indacaterol is a beta2-agonist with high intrinsic efficacy at the receptor level. In preclinical
and in-vitro models it behaves like an almost full agonist … Potency and intrinsic efficacy have …

Indacaterol, a novel inhaled β2-agonist, provides sustained 24-h bronchodilation in asthma

KM Beeh, E Derom, F Kanniess… - European …, 2007 - Eur Respiratory Soc
… FEV 1 ) between indacaterol and placebo 30 … indacaterol 200 and 400 µg meeting pre-specified
efficacy criteria. The mean percentage increases in FEV 1 from placebo with indacaterol