… of reactive oxygen species, release of L-glutamate and activation of caspases are required for oxygen-induced apoptosis of embryonic hippocampal neurons in …

Y Ishikawa, T Satoh, Y Enokido, C Nishio, T Ikeuchi… - Brain research, 1999 - Elsevier
… is a useful in vitro model of neuronal apoptosis to study the molecular … reactive oxygen
species and glutamate in the high (50%) oxygen-induced death of cultured hippocampal neurons. …

From birth to death: A role for reactive oxygen species in neuronal development

C Wilson, E Muñoz-Palma… - Seminars in cell & …, 2018 - Elsevier
… hydrogen peroxide in cultured hippocampal neurons, showing the strong … hippocampus
and cortex of embryonic rat brain homogenates (E18.5) as well as in immature cultured neurons, …

Apoptotic cell death occurs in hippocampal neurons cultured in a high oxygen atmosphere

Y Enokido, H Hatanaka - Neuroscience, 1993 - Elsevier
embryonic rat hippocampal neurons were cultured in a 50% oxygen atmosphere, neurons
… These results indicate that increased levels of oxygen activate an apoptotic mechanism in …

Free radical production and changes in superoxide dismutases associated with hypoxia/reoxygenation-induced apoptosis of embryonic rat forebrain neurons in …

V Lièvre, P Becuwe, A Bianchi, V Koziel… - Free Radical Biology …, 2000 - Elsevier
… initiator of reactive oxygen species [18], [19], [20], [21]. Tan and colleagues [19] have reported
two phases of ROS production in an immortalized mouse hippocampal cell line exposed to …

Reactive oxygen species and the neuronal fate

KAM Kennedy, SDE Sandiford, IS Skerjanc… - Cellular and Molecular …, 2012 - Springer
… provide a brief overview of the process of neurogenesis in the embryo as well as recent
work in the ROS field, focusing on studies supporting a role for ROS in neuronal development. …

Newborn neurons acquire high levels of reactive oxygen species and increased mitochondrial proteins upon differentiation from progenitors

M Tsatmali, EC Walcott, KL Crossin - Brain research, 2005 - Elsevier
… ROS are increased in hippocampal neurons in response to glutamate agonists [10… neurons
from embryonic rat and mouse cortical and hippocampal cultures and directly from embryonic

Comparative analysis of cytosolic and mitochondrial ATP synthesis in embryonic and postnatal hippocampal neuronal cultures

AM Surin, S Khiroug, LR Gorbacheva… - Frontiers in molecular …, 2013 - frontiersin.org
… in cytosol of cultured hippocampal neurons allowed us, for … [ATP]c dynamics in individual
neurons in response to glucose … hippocampal neurons cultivated from E17 to E18 rat embryos, …

Modulation of neuronal stem cell differentiation by hypoxia and reactive oxygen species

HLA Vieira, PM Alves, A Vercelli - Progress in neurobiology, 2011 - Elsevier
embryonic stem cells; the main focus of this review is to summarize the role of oxygen during
neuronal … the number of newborn hippocampal pyramidal neurons after ischemic stroke and …

Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells

M Yoneyama, K Kawada, Y Gotoh, T Shiba… - Neurochemistry …, 2010 - Elsevier
… The primary finding of the present paper is that the proliferation of embryonic hippocampal
NPCs is sensitive to ROS generated endogenously under normal conditions. It has been …

Reactive oxygen species modulate the differentiation of neurons in clonal cortical cultures

M Tsatmali, EC Walcott, H Makarenkova… - Molecular and Cellular …, 2006 - Elsevier
embryonic cortical progenitors. We report that rat cortical progenitors in clonal culture produce
two types of neurons … neurogenic regions such as the hippocampus and olfactory bulb in …