Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
M Delacher, CD Imbusch, D Weichenhan… - Nature …, 2017 - nature.com
… We found that epigenetic modifications defined the molecular characteristics of tissue T reg
cells. Tagmentation-based whole-genome bisulfite sequencing revealed more than 11,000 …
cells. Tagmentation-based whole-genome bisulfite sequencing revealed more than 11,000 …
Long noncoding RNA-mediated maintenance of DNA methylation and transcriptional gene silencing
… states during development, but how these epigenetic states are … DNA methylation is considered
to be a stable epigenetic … These barriers can be either physical in nature, such as DNA-…
to be a stable epigenetic … These barriers can be either physical in nature, such as DNA-…
H3K27me3 is an epigenetic barrier while KDM6A overexpression improves nuclear reprogramming efficiency
C Zhou, Y Wang, J Zhang, J Su, Q An, X Liu… - The FASEB …, 2019 - Wiley Online Library
… effect on the global DNA methylation of bovine embryos. This … the global level of DNA
methylation. We also found that … H3K27me3 is an epigenetic barrier for SCNT reprogramming …
methylation. We also found that … H3K27me3 is an epigenetic barrier for SCNT reprogramming …
Epigenetic activation of meiotic recombination near Arabidopsis thaliana centromeres via loss of H3K9me2 and non-CG DNA methylation
… DNA methylation pathways, for example, via mutation of the H3K9 methyltransferase genes
KYP/SUVH4 SUVH5 SUVH6, or the CHG DNA … non-CG DNA methylation pathway mutants …
KYP/SUVH4 SUVH5 SUVH6, or the CHG DNA … non-CG DNA methylation pathway mutants …
Leukocyte-specific DNA methylation biomarkers and their implication for pathological epigenetic analysis
… Moreover, we show a positive linear relationship between infiltrating leukocytes and DNA
methylation levels at the HOXA3 locus in six cancer types, indicative of further immune cell …
methylation levels at the HOXA3 locus in six cancer types, indicative of further immune cell …
Enzyme-free targeted DNA demethylation using CRISPR–dCas9-based steric hindrance to identify DNA methylation marks causal to altered gene expression
DM Sapozhnikov, M Szyf - Nature Protocols, 2022 - nature.com
… DNA (as in methylated promoter-reporter assays). When choosing to modify DNA methylation
… to increase or decrease DNA methylation and which epigenetic editing technique to use. …
… to increase or decrease DNA methylation and which epigenetic editing technique to use. …
DNA methylation and cancer
M Kulis, M Esteller - Advances in genetics, 2010 - Elsevier
… DNA methylation is associated with histone modifications and the interplay of these epigenetic
… NF-kB, DNA methylation was thought to create a physical barrier, abolishing access to …
… NF-kB, DNA methylation was thought to create a physical barrier, abolishing access to …
[HTML][HTML] DNA methylation in hematopoietic development and disease
AV Gore, BM Weinstein - Experimental hematology, 2016 - Elsevier
… DNA methylation is an important epigenetic modification that can have profound … DNA
methylation plays a critical role in hematopoietic development and hematopoietic disease. DNA …
methylation plays a critical role in hematopoietic development and hematopoietic disease. DNA …
Harnessing epigenetics for breast cancer therapy: The role of DNA methylation, histone modifications, and MicroRNA
J Szczepanek, M Skorupa, J Jarkiewicz-Tretyn… - International Journal of …, 2023 - mdpi.com
… Epigenetic drugs are being tested with increasing frequency, especially those effective in
reversing DNA methylation … of the epigenetic machinery, and especially the synergistic effect of …
reversing DNA methylation … of the epigenetic machinery, and especially the synergistic effect of …
[HTML][HTML] Interchromosomal transfer of epigenetic states in Ascobolus: transfer of DNA methylation is mechanistically related to homologous recombination
V Colot, L Maloisel, JL Rossignol - Cell, 1996 - cell.com
… To investigate whether or not transfer of DNA methylation could also occur between alleles,
we performed a cross between a strain carrying a b2 +mi allele and a strain carrying an …
we performed a cross between a strain carrying a b2 +mi allele and a strain carrying an …