The dynamics of DNA methylation fidelity during mouse embryonic stem cell self-renewal and differentiation
The faithful transmission of DNA methylation patterns through cell divisions is essential for
the daughter cells to retain a proper cell identity. To achieve a comprehensive assessment of …
the daughter cells to retain a proper cell identity. To achieve a comprehensive assessment of …
Dynamic DNA methylation across diverse human cell lines and tissues
… The data described here provide an atlas of DNA methylation for investigating how this
epigenetic mark relates to other molecular and phenotypic characteristics within these diverse …
epigenetic mark relates to other molecular and phenotypic characteristics within these diverse …
Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape
K Day, LL Waite, A Thalacker-Mercer, A West… - Genome biology, 2013 - Springer
… epigenetic drift model is insufficient to explain all age-related changes in DNA methylation.
… Our data show that aging has both dynamic and common influences on DNA methylation. …
… Our data show that aging has both dynamic and common influences on DNA methylation. …
Charting a dynamic DNA methylation landscape of the human genome
… DNA methylation dynamics. In summary, although in theory every CpG can change its
methylation … of cytosine, usually at CpGs, is a common feature of epigenetic regulation of gene …
methylation … of cytosine, usually at CpGs, is a common feature of epigenetic regulation of gene …
Understanding the connection between epigenetic DNA methylation and nucleosome positioning from computer simulations
… Cytosine methylation is one of the most important epigenetic marks that regulate the … effect
of epigenetic DNA methylation on nucleosomal stability using molecular dynamics simulations …
of epigenetic DNA methylation on nucleosomal stability using molecular dynamics simulations …
Tracing dynamic changes of DNA methylation at single-cell resolution
Y Stelzer, CS Shivalila, F Soldner, S Markoulaki… - Cell, 2015 - cell.com
… epigenetic changes into a traceable readout is, to date, a limiting factor in our ability to follow
the dynamics of DNA methylation. … that allow tracing changes in DNA methylation over time. …
the dynamics of DNA methylation. … that allow tracing changes in DNA methylation over time. …
The methylation game: epigenetic and epitranscriptomic dynamics of 5-methylcytosine
A Alagia, M Gullerova - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
… On the other hand, DNA methylation can be actively reversed by family of α-ketoglutarate-…
for the methylated site, and results in loss of the epigenetic mark over several rounds of DNA …
for the methylated site, and results in loss of the epigenetic mark over several rounds of DNA …
[HTML][HTML] The role of DNA methylation in epigenetics of aging
A Unnikrishnan, WM Freeman, J Jackson… - Pharmacology & …, 2019 - Elsevier
… DNA methylation has evolved from one in which methylation patterns are set during development
and generally immutable, to a braoder perspective where DNA methylation … dynamic in …
and generally immutable, to a braoder perspective where DNA methylation … dynamic in …
The emerging role of DNA methylation in epileptogenesis
… Through the latter, DNA methylation dynamics broadly … Epigenetic mechanisms including
DNA methylation regulate not … The importance of epigenetic mechanisms is emphasized by the …
DNA methylation regulate not … The importance of epigenetic mechanisms is emphasized by the …
Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns
E Schneider, G Pliushch, N El Hajj… - Nucleic acids …, 2010 - academic.oup.com
DNA methylation is an epigenetic modification that plays an important role in gene regulation.
It can be influenced by stochastic events, environmental factors and developmental …
It can be influenced by stochastic events, environmental factors and developmental …