DNA methylation: superior or subordinate in the epigenetic hierarchy?

B Jin, Y Li, KD Robertson - Genes & cancer, 2011 - journals.sagepub.com
… participates in the formation of chromatin through interactions with various other epigenetic
… Therefore, we next examine the links between DNA methylation and other epigenetic

Epigenetic Hierarchy within the MAGEA1 Cancer-Germline Gene: Promoter DNA Methylation Dictates Local Histone Modifications

J Cannuyer, A Loriot, GK Parvizi, C De Smet - PloS one, 2013 - journals.plos.org
… relative contribution of DNA methylation and histone acetylation in the epigenetic regulation
of … indicate that DNA methylation has a dominant role in the epigenetic hierarchy governing …

Epigenetic interplay between histone modifications and DNA methylation in gene silencing

T Vaissière, C Sawan, Z Herceg - Mutation Research/Reviews in Mutation …, 2008 - Elsevier
… signal and what is the hierarchical order of epigenetic events during unscheduled gene …
how DNA methylation and histone acetylation communicate to keep the histone–DNA complex …

Epigenetic Hierarchy Governing Nestin Expression

DW Han, JT Do, MJ Araúzo-Bravo, SH Lee… - Stem Cells, 2009 - academic.oup.com
DNA demethylation and histone modifications have been shown to … epigenetic mechanism
governing Nestin transcription. The current study aims to determine whether DNA methylation

Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions

S Lopes, A Lewis, P Hajkova, W Dean… - Human Molecular …, 2003 - academic.oup.com
… Here we examine regional control of DNA methylation in the imprinted Igf2-H19 region in …
linear spreading along the DNA (31). We therefore analysed DNA methylation in the Igf2 …

DNA methylation‐mediated epigenetic control

A Rottach, H Leonhardt, F Spada - Journal of cellular …, 2009 - Wiley Online Library
… are established and maintained by epigenetic processes. Early mechanistic insights came …
states correlate with the DNA methylation level of their promoter region. DNA methylation is a …

DNA methylation: roles in mammalian development

ZD Smith, A Meissner - Nature Reviews Genetics, 2013 - nature.com
DNA methylation and highlight links to other epigenetic modifiers. We then explore, in greater
detail, specific examples in which DNA methylation is … the hierarchy of epigenetic events …

DNA methylation in epigenetic control of gene expression

A Razin, B Kantor - Epigenetics and Chromatin, 2005 - Springer
… The high complexity of the mammalian genome required a multilevel hierarchy of … One of
these levels of regulation involves DNA methylation. DNA methylation is a flexible epigenetic

Epigenetic DNA methylation linked to social dominance

K Lenkov, MH Lee, OD Lenkov, A Swafford… - Plos one, 2015 - journals.plos.org
… Social status hierarchies are ubiquitous in vertebrate social … molecular mechanism such as
DNA methylation might play a role … We show that manipulating global DNA methylation state …

Hierarchical clustering of lung cancer cell lines using DNA methylation markers

AK Virmani, JA Tsou, KD Siegmund, LYC Shen… - … Biomarkers & Prevention, 2002 - AACR
… considerable attention is DNA hypermethylation, which is commonly seen in cancer cells…
Methylation of cytosines at CpG dinucleotides is a natural epigenetic modification of DNA that is …