Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes
CR Farthing, G Ficz, RK Ng, CF Chan, S Andrews… - PLoS …, 2008 - journals.plos.org
… reprogrammed after fertilisation so that the embryo can regain totipotency. This work, therefore,
shows for the first time that epigenetic reprogramming … epigenetically reprogrammed and …
shows for the first time that epigenetic reprogramming … epigenetically reprogrammed and …
[HTML][HTML] Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution
… Aberrant epigenetic reprogramming is assumed to be the … of epigenetic reprogramming
is of particular relevance for the potential therapeutic applications of iPS cells, as epigenetic …
is of particular relevance for the potential therapeutic applications of iPS cells, as epigenetic …
Global epigenetic changes during somatic cell reprogramming to iPS cells
… that fully reprogrammed iPSCs are epigenetically identical to ESCs, and that partially
reprogrammed … This allowed us to follow the epigenetic reprogramming at a single cell level, and …
reprogrammed … This allowed us to follow the epigenetic reprogramming at a single cell level, and …
Rules governing the mechanism of epigenetic reprogramming memory
Aim: Disclosing the mechanisms that regulate reprogramming memory. Materials & methods:
We established computational procedure to find DNA methylation somatic memory sites (…
We established computational procedure to find DNA methylation somatic memory sites (…
Chromatin modification and epigenetic reprogramming in mammalian development
E Li - Nature Reviews Genetics, 2002 - nature.com
… reprogramming during early embryogenesis and gametogenesis, and for tissue-specific gene
expression and global gene … Understanding the process of epigenetic reprogramming in …
expression and global gene … Understanding the process of epigenetic reprogramming in …
Genome-scale epigenetic reprogramming during epithelial-to-mesenchymal transition
… support our conclusion that global reprogramming of chromatin … We next mapped the locations
of H3K36Me3 by ChIP-chip. As … We next mapped H3K4Me3 enrichment by ChIP-chip. As …
of H3K36Me3 by ChIP-chip. As … We next mapped H3K4Me3 enrichment by ChIP-chip. As …
Epigenetic programming and reprogramming during development
I Cantone, AG Fisher - Nature structural & molecular biology, 2013 - nature.com
… Global 'reprogramming' of the epigenetic landscape instead … in which extensive epigenetic
reprogramming takes place. … to adapt genome-wide mapping techniques to the nanoscale …
reprogramming takes place. … to adapt genome-wide mapping techniques to the nanoscale …
[PDF][PDF] Ground state conditions induce rapid reorganization of core pluripotency factor binding before global epigenetic reprogramming
… by global hypomethylation and specific transcriptional profiles, but little is known about
the contributing effectors. Here we show that 2i conditions rapidly alter the global binding …
the contributing effectors. Here we show that 2i conditions rapidly alter the global binding …
Analysis of the epigenetic signature of cell reprogramming by computational DNA methylation profiles
… First, we summarized the global relationships and methylation … Filtered clean reads were
mapped to the hg19 genome … involved in the epigenetic reprogramming of cell differentiation [49…
mapped to the hg19 genome … involved in the epigenetic reprogramming of cell differentiation [49…
Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells
… transcription factors depends on successful epigenetic reprogramming to a pluripotent state.
… This reprogramming process involves global epigenetic remodeling and overcoming similar …
… This reprogramming process involves global epigenetic remodeling and overcoming similar …
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