… intercellular communication as a biological “Rosetta stone” in understanding, in a systems biological manner, stem cell behavior, mechanisms of epigenetic toxicology …
JE Trosko - Journal of Membrane Biology, 2007 - Springer
… Rather, it gives rise to the concept that chemical toxicants act epigenetically; ie, they alter …
to accumulate additional irreversible genetic/epigenetic changes to become an invasive, …
to accumulate additional irreversible genetic/epigenetic changes to become an invasive, …
The gap junction as a “Biological Rosetta Stone”: implications of evolution, stem cells to homeostatic regulation of health and disease in the Barker hypothesis
JE Trosko - Journal of cell communication and signaling, 2011 - Springer
… In effect, epigenetic changes are alterations in the expression of genes at the … “epigenetic
changes” that can lead to heritable changes (which is correct). However, other epigenetic …
changes” that can lead to heritable changes (which is correct). However, other epigenetic …
Mechanisms of Epigenetic Toxicity in the Pathogenesis of Cancer for" Precision Medicine"
JE Trosko - Journal of Cancer Treatment and …, 2018 - cancertreatmentjournal.com
… From the perspective of biological evolution, the transition from single- to multi-cellular … the
“Rosetta Stone” in developing the hypothesis that GJIC plays a major role in the toxicological …
“Rosetta Stone” in developing the hypothesis that GJIC plays a major role in the toxicological …
Modulation of GAP Junctional Communication by “Epigenetic” Toxicants: A Shared Mechanism in Teratogenesis, Carcinogenesis, Atherogenesis, Immunomodulation …
JE Trosko, CC Chang, B Upham - Biomarkers of …, 2002 - api.taylorfrancis.com
… tional, and posttranslational levels (epigenetic toxicology). Both … field of toxicology is the
mechanism of chemically induced … The biological Rosetta Stone idea suggests that by looking at …
mechanism of chemically induced … The biological Rosetta Stone idea suggests that by looking at …
Animal models in translational research: Rosetta stone or stumbling block?
JA Bolker - Bioessays, 2017 - Wiley Online Library
… knowledge of the underlying biological mechanisms; much … along a single dimension such
as potential toxicity.54, 55 … shaped by complex genetic and epigenetic networks. In contrast, …
as potential toxicity.54, 55 … shaped by complex genetic and epigenetic networks. In contrast, …
The promises and challenges of toxico-epigenomics: environmental chemicals and their impacts on the epigenome
… and challenges of using epigenetic biomarkers as an … perspectives on the future role of
epigenetics in toxicology. … limited in identifying biologically relevant epigenetic toxicants. However…
epigenetics in toxicology. … limited in identifying biologically relevant epigenetic toxicants. However…
[图书][B] Epigenetics: the death of the genetic theory of disease transmission
JD Wallach, M Lan, GN Schrauzer - 2014 - books.google.com
The book EPIGENETICS is a global update of Darwin's book The Origin of Species. There is
no other book that embraces all of the events (political, socially, biologically, nutritionally, …
no other book that embraces all of the events (political, socially, biologically, nutritionally, …
From Radiation Genetics, Mutagenesis, Gap Junctions, Epigenetics, Stem Cells and an Integration of Radiation and Chemical Carcinogenesis
JE Trosko - Radiation Research, 2024 - meridian.allenpress.com
… the epigenetic toxicological effects. These are strategies to prevent the toxic effects of any …
, being a “Rosetta Stone” symbol, is what allowed me to see how radiation biology (ionizing, …
, being a “Rosetta Stone” symbol, is what allowed me to see how radiation biology (ionizing, …
Preserving human potential as freedom: a framework for regulating epigenetic harms
F Khan - Health Matrix, 2010 - HeinOnline
… a Rosetta Stone unlocking the mysteries of heredity and disease; it was evident that a tremendous
amount of bio… cases were explained as a case of fetal toxicity. However, in most cases, …
amount of bio… cases were explained as a case of fetal toxicity. However, in most cases, …
[PDF][PDF] Pre-Natal Epigenetic Influences on Acute and Chronic Diseases Later in Life, such as Cancer: Global Health Crises Resulting from a Collision of Biological and …
JE Trosko - Journal of Food Science and Nutrition, 2011 - Citeseer
… mechanisms, the primary cause is via “epigenetic”, or altered gene expression, modifications
… adult stem cells during early development by epigenetic chemicals could either increase or …
… adult stem cells during early development by epigenetic chemicals could either increase or …
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