… Epigenetic modifications were reported to play an important … of epigenetic machinery, but
are also epigenetically modified … genes shown to be epigenetically regulated in association …

… , epigenetic toxicity must be incorporated in toxicity testing. Because modulation of gap
junctional intercellular communication by epigenetic … intracellular signaling to trigger epigenetic …

… epigenetics in toxicology, and provides information on several relevant aspects: (1)
disease-associated epigenetic … epigenetic condition and transferring epigenetic signals. Many of …

… hypersensitive to IR, with the benefit of decreased toxicity; furthermore, it is possible that local
… , has attracted greater attention to genetic and epigenetic susceptibility to cancer, possibly …

… One of the unanswered questions in toxicology is to what degree carcinogens affect the …
and there is cross-talk between the intracellular signalling pathways mediated by the E2 and IGF-…

… Epigenetic regulation by nanomaterials, effects of nanoparticle-protein interactions on cell
signaling … interacting networks and upstream signaling pathways of toxicity responses but also …

… Signal transduction pathways Signal transduction pathways transmit extracellular signals,
via an intracellular series of signaling molecules into gene. Cellular processes such as …

… Today, our knowledge includes the facts both that epigenetic events play a major role in
carcinogenesis and that low-dose radiation can also induce epigenetic events in and between …

… receptor activation, which can trigger intracellular signalling pathways such as MAPK, nuclear
factor kappa B (NFκB), and Janus kinase/signal transducer and activator of transcription (…

… (1–3 days) is able to epigenetically silence target genes placed near heterochromatin, while
… In addition to epigenetic effects, nickel compounds activate hypoxia signaling pathways. …