In spite of the early speculation by Loewenstein that one of the critical distinguishing
phenotypes of cancers from normal cells was the dysfunction of gap junctional intercellular …

… In effect, epigenetic changes are alterations in the expression of genes at the … “epigenetic
changes” that can lead to heritable changes (which is correct). However, other epigenetic …

… tional, and posttranslational levels (epigenetic toxicology). Both … field of toxicology is the
mechanism of chemically induced … The biological Rosetta Stone idea suggests that by looking at …

The book EPIGENETICS is a global update of Darwin's book The Origin of Species. There is …
EPIGENETICS is required reading for the very survival of Americans and yes all of humanity-…

… Early observations by Werner Loewenstein 91 represented the “Rosetta Stone” in developing
the hypothesis that GJIC plays a major role in the toxicological mechanism of many human …

… as epigenetic disruptors. We also discuss the advantages and challenges of using epigenetic
… risk assessment, and our perspectives on the future role of epigenetics in toxicology. …

… the epigenetic toxicological effects. These are strategies to prevent the toxic effects of any
epigenetic … This concept of gap junctional intercellular communication, being a “Rosetta Stone” …

Since their discovery twenty years ago and prospective isolation a decade later, neural
stem cells (NSCs), their progenitors, and differentiated cell derivatives along with other stem-cell …

… Mapping human DNA did not turn out to be a Rosetta Stone unlocking the mysteries of heredity
… Lack of toxicological or material safety data is a problem that undermines many potential …

… This challenge is not that mutations do not play roles in human-inherited or somatic diseases
but that chemical exposures bring about disease end points by epigenetic mechanisms or …