[HTML][HTML] Lung CD4+ resident memory T cells remodel epithelial responses to accelerate neutrophil recruitment during pneumonia

AT Shenoy, GA Wasserman, EI Arafa, AK Wooten… - Mucosal …, 2020 - Elsevier
… roles for other CD4 + cells in quickly remodeling epithelial responses in the lung. Perhaps
… endothelial cells could be an approach for future studies to eliminate lung CD4 + T RM cells

Developmental plasticity allows outside-in immune responses by resident memory T cells

…, H Borges da Silva, V Vezys, B Youngblood… - Nature …, 2020 - nature.com
… Fully differentiated T RM cells isolated from small intestine epithelium exhibited … T CM cells,
effector memory T cells and T RM cells on recall. Ex-T RM cells, former intestinal T RM cells

Niches for the long-term maintenance of tissue-resident memory T cells

S Takamura - Frontiers in immunology, 2018 - frontiersin.org
… that T RM cells comprise the majority of memory T cells in the … These cells are part of a
comprehensive memory response … recruitment of CD8 + T cells to the epithelial tissues by antigen-…

Interstitial-resident memory CD8+ T cells sustain frontline epithelial memory in the lung

…, T Masumoto, A Katsushima, T Nakayama… - Journal of Experimental …, 2019 - rupress.org
… The later phases of the recall response are mediated by central memory T cells that
survey secondary lymphoid organs and are activated in the draining lymph nodes. These …

Resident memory T cells, critical components in tumor immunology

F Mami-Chouaib, C Blanc, S Corgnac, S Hans… - … for immunotherapy of …, 2018 - Springer
T RM cells within epithelial tumor islets. The intra-epithelial location of CD103 + CD8 + T cells
… -VLA-1 blocking antibodies at the memory phase of the immune response [34], as well as …

Tissue-resident memory T cells: local specialists in immune defence

SN Mueller, LK Mackay - Nature Reviews Immunology, 2016 - nature.com
… Effector T cells that enter the skin can: enter epithelial cell … Tissue-resident memory T cells
(T RM cells) are poised to respond … The early phase of local immunity in epithelial tissues (for …

Tissue-Resident Memory CD8+ T Cells: From Phenotype to Function

DJ Topham, EC Reilly - Frontiers in immunology, 2018 - frontiersin.org
… + T cells responding to oral Listeria infection due to a defect in initial accumulation (47). Since
epithelial cells … expressed on the T cells in close proximity to the epithelial cells and not in …

Dynamic T cell migration program provides resident memory within intestinal epithelium

D Masopust, D Choo, V Vezys, EJ Wherry… - Journal of Experimental …, 2010 - rupress.org
… that memory T cells within small intestine epithelium do not routinely recirculate with memory
T cells … these findings by demonstrating that T cells activated in vivo in response to a viral or …

Tissue-Resident-Memory CD8+ T Cells Bridge Innate Immune Responses in Neighboring Epithelial Cells to Control Human Genital Herpes

T Peng, K Phasouk, CN Sodroski, S Sun… - Frontiers in …, 2021 - frontiersin.org
… Here, we report that epithelial cells neighboring CD8TRM display an enhanced antiviral …
and cell-intrinsic immunity in surrounding epithelial cells to provide tissue-wide resistance and …

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

…, WR Heath, FR Carbone, T Gebhardt - Proceedings of the …, 2012 - National Acad Sciences
… Given the limited ability of circulating memory T cells to … whether we could embed memory
T cells in peripheral sites in the … T cells during the memory phase of the immune response. …