The epitranscriptomic mechanism of metal toxicity and carcinogenesis

C Yang, Z Wang - International Journal of Molecular Sciences, 2022 - mdpi.com
… to metals causes epitranscriptomic dysregulations, … mechanisms responsible for metal
toxicity and carcinogenesis. The goals of this review are to briefly introduce epitranscriptomics and …

Environmental epitranscriptomics

A Cayir, HM Byun, TM Barrow - Environmental Research, 2020 - Elsevier
… organisms to date, collectively known as the ‘epitranscriptome’, with 6-methyladenosine (m
6 A), 5-… how environmental exposures affect the epitranscriptome and how this may mediate …

The role of epigenetic and epitranscriptomic modifications in plants exposed to non-essential metals

J Chmielowska-Bąk, IR Searle, TN Wakai… - Frontiers in Plant …, 2023 - frontiersin.org
Metal toxicity depends on a range of mechanisms at the cellular level. The most-… and
epitranscriptomic changes in plants driven by metals, with special emphasis on their role in metal

Emerging roles of N6-methyladenosine (m6A) epitranscriptomics in toxicology

E Malovic, A Ealy, A Kanthasamy… - Toxicological …, 2021 - academic.oup.com
… including heavy metals, pesticides, and other toxic pollutants… As we will discuss herein, we
think m6A epitranscriptomics is … understanding molecular mechanisms of toxicopathogenesis, …

Epigenetic and epitranscriptomic mechanisms of chromium carcinogenesis

Z Wang, C Yang - Advances in Pharmacology, 2023 - Elsevier
… epigenetic and epitranscriptomic changes could play … epitranscriptomic effects of Cr(VI)
exposure and discuss their roles in Cr(VI) carcinogenesis. Better understanding the mechanism

Global N6-methyladenosine profiling of cobalt-exposed cortex and human neuroblastoma H4 cells presents epitranscriptomics alterations in neurodegenerative …

J Tang, C Zheng, F Zheng, Y Li, Y Wang… - Environmental …, 2020 - Elsevier
… on the nervous system, but its detailed mechanisms of neurotoxicity have yet to be determined.
In … for broadening the epigenetic regulatory mechanism of RNA induced by heavy metals. …

RNA m6A Alterations Induced by Biomineralization Nanoparticles: A Proof-of-Concept Study of Epitranscriptomics for Nanotoxicity Evaluation

J Pan, J Wang, K Fang, W Hou, B Li, J Zhao… - Nanoscale Research …, 2022 - Springer
… -based approaches are capable of mapping the toxicity-related molecular pathways and
biological … its potential biological mechanisms. We found that BSA-templated NPs could induce …

RNA m6A Alterations Induced by Biomineralization Nanoparticles: A Proof-of-Concept Study of Epitranscriptomics for Nanotoxicity Evaluation

P Jinbin, W Jiaojiao, F Kun, H Wenjing… - Nanoscale …, 2022 - search.proquest.com
… study the nanotoxicity in terms of epitranscriptomics. These NPs … b Schematic diagram of the
epitranscriptomic nanotoxicity … mechanisms. We found that BSA-templated NPs could induce …

Dynamic N6-methyladenosine RNA methylation landscapes reveal epi-transcriptomic modulation induced by ammonia nitrogen exposure in the Pacific whiteleg …

Y Lei, Z Yuan, Q Zeng, B Wan, J Liu, W Wang - Journal of Hazardous …, 2023 - Elsevier
… and epi-transcriptomic modulation in ammonia stress response of L. vannamei, and provide
more insight into the molecular mechanisms of physiological tolerance of ammonia toxicity

Profile of N6-methyladenosine of Pb-exposed neurons presents epitranscriptomic alterations in PI3K-AKT pathway-associated genes

S Ai, D Li, X Gu, Y Xu, Y Wang, HL Wang… - Food and Chemical …, 2023 - Elsevier
… a pervasive heavy metal with multi-organ toxicity. However, the molecular mechanisms of
Pb… The dynamics of N6-methylademine (m6A) is an emerging regulatory mechanism for gene …