[PDF][PDF] Malignancies associated with epstein-barr virus: pathobiology, clinical features, and evolving treatments

N Neparidze, J Lacy - Clin Adv Hematol Oncol, 2014 - hematologyandoncology.net
… Clinical implications of plasma EpsteinBarr virus DNA in early-stage extranodal nasal-type
NK/T… Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific …

Epstein-Barr virus—recent advances

KF Macsween, DH Crawford - The Lancet infectious diseases, 2003 - thelancet.com
Epstein-Barr virus (EBV; figure 1) has co-evolved with human beings over millions of years
and during this long association the virus life cycle has become supremely adapted to its …

… of Epstein-Barr virus-associated posttransplant lymphoproliferative diseases: implications for understanding their pathogenesis and developing rational treatment …

DW Hanto, MD, Ph. D - Annual review of medicine, 1995 - annualreviews.org
… cell clone, therebypreventing evolution to a monoclonal lymphoma… The independent evolution
of these unregulated B-cell … clonal cytogeneticabnormalities suggests that evolution from a …

EpsteinBarr virus: more than 50 years old and still providing surprises

LS Young, LF Yap, PG Murray - Nature reviews cancer, 2016 - nature.com
… It is more than 50 years since the EpsteinBarr virus (EBV), the first human tumour virus,
was … insights at the molecular level in the diagnosis, treatment and prevention of cancer. …

Epstein Barr virus: development of vaccines and immune cell therapy for EBV-associated diseases

X Cui, CM Snapper - Frontiers in Immunology, 2021 - frontiersin.org
treatment of cancers. Adoptive T-cell therapy has been successfully used in the prevention
and treatment … EBV reactivation, termed PTLD that can evolve into Hodgkin lymphoma or non-…

Epstein-Barr virus (EBV) reactivation and therapeutic inhibitors

JR Kerr - Journal of clinical pathology, 2019 - jcp.bmj.com
… , including drugs licensed for treatment of other herpesviruses, … EBV proteins, Epstein-Barr
nuclear antigens EBNA3, EBNA4 … But how they arise and evolve during primary EBV infection …

Clinical features and treatment strategies of EpsteinBarr virus-associated hemophagocytic lymphohistiocytosis

S Imashuku - Critical reviews in oncology/hematology, 2002 - Elsevier
… In this sense, the initial treatment of EBV-HLH should be similar to the treatment of systemic
… , the treatment objective is to abrogate the inflammatory cascade. For this kind of treatment to …

Epstein-Barr virus: the impact of scientific advances on clinical practice

H Williams, DH Crawford - Blood, 2006 - ashpublications.org
Epstein-Barr virus (EBV) is a tumorigenic herpes virus that infects and persists in B
lymphocytes in the majority of humans, generally without causing disease. However, in a few …

EpsteinBarr virus in multiple sclerosis: theory and emerging immunotherapies

A Bar-Or, MP Pender, R Khanna, L Steinman… - Trends in molecular …, 2020 - cell.com
… demonstrating a link between B cell-tropic EpsteinBarr virus (EBV) and disease onset.
Efforts to develop antiviral strategies for treating MS are underway. Although gaps remain in our …

Epstein-Barr virus infections: biology, pathogenesis, and management

SE Straus, JI Cohen, G Tosato… - Annals of internal medicine, 1993 - acpjournals.org
… virus (EBV) is a ubiquitous pathogen that has evolved an effective strategy for infection, …
no clinical benefit in treating uncomplicated acute infectious mononucleosis with acyclovir. …