Emerging therapeutic targets for sepsis
EW Tindal, BE Armstead, SF Monaghan… - … on therapeutic targets, 2021 - Taylor & Francis
… Benefits of probiotic treatment prior to experimental sepsis included reduced mortality as
well as a decrease in inflammatory cytokines IL-2 and IL-22 when compared to saline treated …
well as a decrease in inflammatory cytokines IL-2 and IL-22 when compared to saline treated …
Experimental therapeutic strategies for severe sepsis: mediators and mechanisms
WR Parrish, M Gallowitsch‐Puerta… - Annals of the New …, 2008 - Wiley Online Library
… mortality rate of severe sepsis suggests that the need for additional therapies is high. Clinical
… potential therapeutic targets that may be exploited in the future treatment of severe sepsis. …
… potential therapeutic targets that may be exploited in the future treatment of severe sepsis. …
Intracellular lipopolysaccharide sensing as a potential therapeutic target for sepsis
A Pfalzgraff, G Weindl - Trends in Pharmacological Sciences, 2019 - cell.com
… that targets the underlying mechanism of sepsis. During the last decades therapies developed
… development strategies for the treatment of sepsis and septic shock need to be revisited [ …
… development strategies for the treatment of sepsis and septic shock need to be revisited [ …
Novel therapeutic targets for sepsis: regulation of exaggerated inflammatory responses
… experimental basic studies have been undergone to identify the effective therapy for sepsis
and these novel therapies … shed light on novel therapeutic targets for the treatment of sepsis. …
and these novel therapies … shed light on novel therapeutic targets for the treatment of sepsis. …
Therapeutic targets in sepsis: past, present, and future
EJ Seeley, GR Bernard - Clinics in Chest Medicine, 2016 - chestmed.theclinics.com
… therapies failed in human trials. In addition, this article examines potential future sepsis targets
and … The mice included in these experiments are often 8 to 12 weeks old and they are not …
and … The mice included in these experiments are often 8 to 12 weeks old and they are not …
Therapeutic potential of HMGB1-targeting agents in sepsis
… of experimental sepsis, and discuss the therapeutic potential of several HMGB1-targeting …
Although HMGB1 appears to be a feasible therapeutic target for experimental sepsis (Refs …
Although HMGB1 appears to be a feasible therapeutic target for experimental sepsis (Refs …
Therapeutic interventions in sepsis: current and anticipated pharmacological agents
… as well as deliver therapeutic agents to targeted tissues and … new experimental and clinical
approaches for therapeutic … The ER-β is an important therapeutic target because it is not …
approaches for therapeutic … The ER-β is an important therapeutic target because it is not …
Immunometabolism: another road to sepsis and its therapeutic targeting
V Kumar - Inflammation, 2019 - Springer
… dysregulated immune response during sepsis and plays a very … during sepsis to design
future target-based therapeutics … sepsis and its targeting as a future therapeutic approach. …
future target-based therapeutics … sepsis and its targeting as a future therapeutic approach. …
Novel therapeutic targets for prevention and therapy of sepsis associated acute kidney injury
CH Pelte, LS Chawla - Current drug targets, 2009 - ingentaconnect.com
… in patients who are septic. These … sepsis is supported by the fact that acute tubular necrosis
(ATN) is an uncommon finding in histopathologic studies of human and experimental septic …
(ATN) is an uncommon finding in histopathologic studies of human and experimental septic …
Recent developments in the identification of novel therapeutic targets for the treatment of patients with sepsis and septic shock
J Cohen - Scandinavian journal of infectious diseases, 2003 - Taylor & Francis
… in an experimental model of gram-negative peritoneal sepsis and … recently as an interesting
potential therapeutic target (15). … anti-toxin therapy. This is certainly true in the case of …
potential therapeutic target (15). … anti-toxin therapy. This is certainly true in the case of …
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