The gene expression response of breast cancer to growth regulators: patterns and correlation with tumor expression profiles
… disease progression rather than growth factor signaling. This article highlights the overall
impact at the gene expression level of diverse regulators of breast cancer growth and links the …
impact at the gene expression level of diverse regulators of breast cancer growth and links the …
Progranulin Gene Expression Regulates Epithelial Cell Growth and Promotes Tumor Growth in Vivo
Z He, A Bateman - Cancer research, 1999 - AACR
… gene expression to maintain malignancy. Here we show that as well as requiring the gene
product, elevating progranulin gene expression … Epithelial tumors are thought to originate as …
product, elevating progranulin gene expression … Epithelial tumors are thought to originate as …
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
PH Maxwell, GU Dachs, JM Gleadle… - Proceedings of the …, 1997 - National Acad Sciences
… in gene expression, vascularity, and growth between the tumor … tumors is appropriate for
HIF-1 activation, and that this has an … function in determining tumor angiogenesis and growth. …
HIF-1 activation, and that this has an … function in determining tumor angiogenesis and growth. …
A novel gene expression profile in lymphatics associated with tumor growth and nodal metastasis
S Clasper, D Royston, D Baban, Y Cao, S Ewers… - Cancer Research, 2008 - AACR
… growth factor (VEGF)-C fibrosarcomas implanted in C57BL/6 mice. Our findings reveal significant
differences in expression of some 792 genes … matrix, and vessel growth/patterning. The …
differences in expression of some 792 genes … matrix, and vessel growth/patterning. The …
PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis
K Bhalla, BJ Hwang, RE Dewi, L Ou, W Twaddel… - Cancer research, 2011 - AACR
… loss of PGC1α expression showed that PGC1α also promotes tumor growth. Interestingly, …
cycle gene expression, we also observed an increase in the expression of two genes required …
cycle gene expression, we also observed an increase in the expression of two genes required …
Tumor growth modulation by sense and antisense vascular endothelial growth factor gene expression: effects on angiogenesis, vascular permeability, blood volume …
T Oku, JG Tjuvajev, T Miyagawa, T Sasajima, A Joshi… - Cancer research, 1998 - AACR
… tumor angiogenesis and tumor growth. We evaluated the effect of VEGF expression on the
pathophysiology of tumor growth in … , with minimal VEGF expression, were stably transfected …
pathophysiology of tumor growth in … , with minimal VEGF expression, were stably transfected …
The von Hippel–Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C
… To investigate whether this would promote or suppress tumor growth, we compared the
growth … As reported, expression of pVHL did not affect the 786-O cells growth under standard …
growth … As reported, expression of pVHL did not affect the 786-O cells growth under standard …
Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1α enhances hypoxic gene expression and tumor growth
AJ Krieg, EB Rankin, D Chan… - … and cellular biology, 2010 - Taylor & Francis
… tumor growth in vivo, demonstrating that histone demethylation plays a significant role in
modulating growth within the tumor … gene expression, ultimately enhancing tumor growth. …
modulating growth within the tumor … gene expression, ultimately enhancing tumor growth. …
[HTML][HTML] Gene expression profiling of the tumor microenvironment during breast cancer progression
XJ Ma, S Dahiya, E Richardson, M Erlander… - Breast cancer …, 2009 - Springer
… -associated stroma is activated by the malignant epithelial cells to foster tumor growth – for
example, by secreting growth factors, increasing angiogenesis, and facilitating cell migration, …
example, by secreting growth factors, increasing angiogenesis, and facilitating cell migration, …
Modulation of gene expression and tumor cell growth by redox modification of STAT3
L Li, S Cheung, EL Evans, PE Shaw - Cancer research, 2010 - AACR
… gene expression The effect of ROS on STAT3-dependent gene expression was examined
with reporter genes … yielded low levels of IL-6–inducible expression. Cotransfection of an …
with reporter genes … yielded low levels of IL-6–inducible expression. Cotransfection of an …
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