Principles and challenges of genome-wide DNA methylation analysis

PW Laird - Nature Reviews Genetics, 2010 - nature.com
… -base-pair resolution whole-genome DNA methylation analysis 22,23,24 . Many of the
high-resolution genome-wide DNA methylation profiling techniques were pioneered in model …

[HTML][HTML] Profiling genome-wide DNA methylation

WS Yong, FM Hsu, PY Chen - Epigenetics & chromatin, 2016 - Springer
… background of DNA methylation and its pattern in plants, animals and fungi. We present an
overview of major experimental approaches to profiling genome-wide DNA methylation and …

[HTML][HTML] methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

A Akalin, M Kormaksson, S Li, FE Garrett-Bakelman… - Genome biology, 2012 - Springer
DNA methylation is a chemical modification of cytosine bases that is pivotal for gene … ,
thatrapidly analyzes genome-wide cytosine epigenetic profiles from high-throughput methylation

Quantitative comparison of genome-wide DNA methylation mapping technologies

C Bock, EM Tomazou, AB Brinkman, F Müller… - Nature …, 2010 - nature.com
DNA methylation mapping by four methods Genome-wide DNA methylation mapping is
most commonly used as a discovery tool to identify differentially methylated regions (DMRs) as …

Genomewide DNA methylation profiling

M Bibikova, JB Fan - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
DNA methylation plays a critical role in the regulation of gene expression. The ability to access
the methylation status for a … Microarray and sequencing‐based DNA methylation profiling …

Advances in genome-wide DNA methylation analysis

R Gupta, A Nagarajan, N Wajapeyee - Biotechniques, 2010 - Future Science
… of new technologies to advance the study of DNA methylation. Here, we review these … to
genome-wide DNA methylation profiling and also discuss a newly identified DNA methylation

Nightshift work and genome-wide DNA methylation

P Bhatti, Y Zhang, X Song, KW Makar… - Chronobiology …, 2015 - Taylor & Francis
… in DNA methylation, particularly in the circadian genes. Using the Infinium HumanMethylation450
Bead Array (Illumina, San Diego, CA), we compared genome-wide methylation

Genome-wide analysis of DNA methylation patterns

D Zilberman, S Henikoff - 2007 - journals.biologists.com
… that, either currently or in the near future, can be used by any laboratory to perform
genome-wide DNA methylation analyses: DNA microarrays and high-throughput DNA sequencing. …

Genome-wide DNA methylation profiling using Infinium® assay

M Bibikova, J Le, B Barnes, S Saedinia-Melnyk… - …, 2009 - Taylor & Francis
… Moreover, tissue-specific methylation (variation in methylation across tissues) was much …
Conclusion: Our results demonstrate a genome-wide scalable array-based methylation readout …

[HTML][HTML] DNA methylation and body-mass index: a genome-wide analysis

KJ Dick, CP Nelson, L Tsaprouni, JK Sandling, D Aïssi… - The Lancet, 2014 - thelancet.com
… We undertook a genome-wide analysis of methylation at CpG sites in relation to BMI. … 1 Mb
of cg22891070 and methylation at this probe, using the genome-wide SNP data available for …