… of imprinted genes. This review describes possible mechanisms by which DNA methylation
can regulate gene expression, using imprinted genes as examples. The molecular basis of …

… that DNA methylation plays a critical role in genomic imprinting. Specifically, DNA methylation
is required for the maintenance of monoallelic expression of imprinted genes. Our data do …

Studies in adrenocortical cells have implicated the orphan nuclear receptor SF-1 in the
gene regulation of the steroid hydroxylases. We used targeted disruption of the Ftz-F1 gene, …

… genes such as imprinted and X-linked genes. Our results clearly establish that DNA methylation
plays a critical role in genomic imprinting. More specifically, DNA methylation is required …

… modification which can affect gene expression, DNA methylation has been an attractive …
genomic imprinting. Many correlations in mice and humans link allele-specific DNA methylation …

… imprinted DNA methylation (see Tables 1 and 2 for examples of a … methylated locus,
H19, and for a maternally methylated locus, Igf2r), the kinetics and levels of DNA methylation …

… of genomic imprinting, which is linked to alterations in methylation. Indeed epigenetic and
… We suggest that genomic imprinting be defined broadly as an epigenetic modification that is …

… involve altered genomic imprinting because we had mapped the gene to 11p15. 5 by genetic
linkage analysis in families (81); this region is homologous to a known imprinted region of …

… gene expression. We used comparative analysis to investigate the origin of genomic imprinting
… PEG10 (paternally expressed 10) is a retrotransposon-derived imprinted gene that has …

… One model system that contributed a foundation for these studies is the process of genomic
imprinting. DNA methylation is a process whereby a methyl (CH 3 ) group is added most …