Glycosylation in cancer: its application as a biomarker and recent advances of analytical techniques

Y Haga, K Ueda - Glycoconjugate Journal, 2022 - Springer
glycosylation is well defined as a hallmark of cancer and … in analytical technologies allow
us to analyze cancer-specific … A number of glycan analysis techniques, such as lectin-based …

Mass spectrometry methods for studying glycosylation in cancer

H Osório, CA Reis - Mass spectrometry data analysis in proteomics, 2013 - Springer
… , cancer cell invasion, and metastization. Cancer is associated with glycosylation alterations
both … Glycosylation changes on glycoconjugates either present on the surface or secreted by …

N-glycosylation of colorectal cancer tissues: a liquid chromatography and mass spectrometry-based investigation

CIA Balog, K Stavenhagen, WLJ Fung… - Molecular & Cellular …, 2012 - ASBMB
… investigated N-glycosylation changes occurring in colorectal cancer tumor tissues, and to
that end we determined the N-glycan profiles from 13 colorectal cancer tumor tissue samples …

Glycosylation and liver cancer

A Mehta, H Herrera, T Block - Advances in cancer research, 2015 - Elsevier
… Alterations in glycosylation have long been associated with cancer. In the case of HCC,
the first major changes identified included the core fucosylation of AFP, the primary serum …

Glycosylation characteristics of colorectal cancer

S Holst, M Wuhrer, Y Rombouts - Advances in cancer research, 2015 - Elsevier
… of cancer biology. We here describe the change of glycosylation specifically defining colorectal
cancer … , and glycosphingolipid glycans in colorectal cancer cells and tissues as well as …

The role of glycosylation in breast cancer metastasis and cancer control

AC Kölbl, U Andergassen, U Jeschke - Frontiers in oncology, 2015 - frontiersin.org
… With the development of new analytical techniques, new insights were gained on the … aberrant
glycosylation within. Mucin-1 and Galectin were recognized as key players in glycosylation

Glycosylation‐based serum biomarkers for cancer diagnostics and prognostics

A Kirwan, M Utratna, ME O'Dwyer… - BioMed research …, 2015 - Wiley Online Library
… to cancer diagnostics, monitoring, and prognostics. Glycosylation-based cancer biomarkers
which … of high throughput (HTP) and other emerging analytical techniques, are described. …

Aberrant glycosylation and cancer biomarker discovery: a promising and thorny journey

M Wang, J Zhu, DM Lubman, C Gao - Clinical Chemistry and …, 2019 - degruyter.com
… However, combined with laser-induced FLD (LIF), CE-based methods have become a
powerful analytic technique, not merely a separation method, for carbohydrate characterization …

Protein glycosylation investigated by mass spectrometry: an overview

A Illiano, G Pinto, C Melchiorre, A Carpentieri, V Faraco… - Cells, 2020 - mdpi.com
… Although the examination of changes in glycosylation in cancer lesions poses unique
challenges, recent developments in glycomics offer promising solutions and may reveal specific …

Cell surface protein glycosylation in cancer

MN Christiansen, J Chik, L Lee, M Anugraham… - …, 2014 - Wiley Online Library
cancer 3, possibly due to dysregulated transcription of enzymes of the glycosylation
machinery. Many studies have shown that altered glycosylation patterns on the surface of cancer