Erlotinib in cancer treatment
MA Bareschino, C Schettino, T Troiani, E Martinelli… - Annals of oncology, 2007 - Elsevier
… growth factor (EGF) belongs to a family of related peptides (EGF-like growth factor), which
include transforming growth factor o (TGFo… EGF-like growth factors bind to activate one or more …
include transforming growth factor o (TGFo… EGF-like growth factors bind to activate one or more …
Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib
DA Haas-Kogan, MD Prados, T Tihan… - Journal of the …, 2005 - academic.oup.com
… from tissue resected 68 days after the initiation of erlotinib treatment, after the patient was
off study and no longer treated with erlotinib. There was not sufficient tissue to complete all …
off study and no longer treated with erlotinib. There was not sufficient tissue to complete all …
[HTML][HTML] Clinical utility of epidermal growth factor receptor expression for selecting patients with advanced non-small cell lung cancer for treatment with erlotinib
GM Clark, DM Zborowski, JL Culbertson… - Journal of Thoracic …, 2006 - Elsevier
… Erlotinib (Tarceva®) has demonstrated a survival benefit in … erlotinib, epidermal growth
factor receptor (EGFR) protein expression may provide a basis for selecting patients for treatment …
factor receptor (EGFR) protein expression may provide a basis for selecting patients for treatment …
Correlation between development of rash and efficacy in patients treated with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib in two large phase …
B Wacker, T Nagrani, J Weinberg, K Witt, G Clark… - Clinical Cancer …, 2007 - AACR
… of rash during treatment with the epidermal growth factor receptor inhibitor erlotinib and
improved … (single agent in non–small-cell lung cancer, n = 444 in erlotinib group and n = 229 in …
improved … (single agent in non–small-cell lung cancer, n = 444 in erlotinib group and n = 229 in …
A review of erlotinib and its clinical use
PA Tang, MS Tsao, MJ Moore - Expert opinion on pharmacotherapy, 2006 - Taylor & Francis
… growth factor receptor expression and mutation status. This article reviews the current clinical
status of erlotinib… in survival associated with erlotinib treatment, as compared with placebo, …
status of erlotinib… in survival associated with erlotinib treatment, as compared with placebo, …
[HTML][HTML] Use of the epidermal growth factor receptor inhibitors gefitinib and erlotinib in the treatment of non-small cell lung cancer: a systematic review
R Feld, SS Sridhar, FA Shepherd, JA Mackay… - Journal of Thoracic …, 2006 - Elsevier
… cell carcinoma; erlotinib; gefitinib; and epidermal growth factor receptor were combined with
… cell lung; Iressa; gefitinib; ZD1839; Tarceva; erlotinib; OSI774; and EGFR-TK. These terms …
… cell lung; Iressa; gefitinib; ZD1839; Tarceva; erlotinib; OSI774; and EGFR-TK. These terms …
18F-FDG PET/CT for monitoring treatment responses to the epidermal growth factor receptor inhibitor erlotinib
MR Benz, K Herrmann, F Walter… - Journal of Nuclear …, 2011 - Soc Nuclear Med
… to undergo erlotinib treatment were … start of erlotinib treatment can identify erlotinib responders
and nonresponders. These findings are relevant because early identification of treatment …
and nonresponders. These findings are relevant because early identification of treatment …
Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non–small-cell lung cancer treated with …
DA Eberhard, BE Johnson, LC Amler… - Journal of clinical …, 2005 - ascopubs.org
… growth factor receptor (EGFR) mutations have been associated with tumor response to
treatment … The implications of EGFR mutations in patients treated with EGFR inhibitors plus first-…
treatment … The implications of EGFR mutations in patients treated with EGFR inhibitors plus first-…
… of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib
F Morgillo, JK Woo, ES Kim, WK Hong, HY Lee - Cancer research, 2006 - AACR
… Role of IGF-IR signaling pathways in the development of resistance to erlotinib treatment
in NSCLC cells. To investigate the mechanisms involved in the sensitivity of NSCLC cells to …
in NSCLC cells. To investigate the mechanisms involved in the sensitivity of NSCLC cells to …
Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva)
P Chinnaiyan, S Huang, G Vallabhaneni, E Armstrong… - Cancer research, 2005 - AACR
… Erlotinib (Tarceva) is an orally available HER1 (epidermal growth factor receptor, EGFR)
tyrosine kinase inhibitor advancing through clinical trials for the treatment of a range of human …
tyrosine kinase inhibitor advancing through clinical trials for the treatment of a range of human …
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