… clinical trials of novel therapies for hospitalized heart failure (HHF) have failed to improve the
… These limitations result in 2 notable problems for drug development. The first is challenges …

… Ideally, a precise hospitalized HF subpopulation at particularly … events affecting hospitalized
patients with HF is needed. … Acute Heart Failure) trial, which randomized 1,161 hospitalized …

… and resulting in more than 1 million hospitalizations annually in both the United States and
… discovery of multiple evidence-based drug and device therapies, hospitalized heart failure (…

… This article summarizes concepts in developing therapies for HHF discussed during a
multidisciplinary panel at the Heart Failure Society of America's Annual Scientific Meeting, …

… , monitoring and managing patients showed improved clinical outcomes, including reduced
hospitalisation for heart failure. One limitation of the trial is that the control group did not have …

… Among patients who are hospitalized with heart failure (HF), worsening renal function (WRF)
is … whether acute treatment for patients who were hospitalized with HF contributes to WRF. …

… There are more than a million hospitalizations for heart failure (HHF) annually in the United
States 1 and >80% of them occur in patients with known chronic heart failure (HF). These …

… This paper aims to summarize the work of the Heart Failure Collaboratory over the past 7 …
, HF drug development programs focused on clinical outcomes such as hospitalization and …

… days of discharge for patients hospitalized with heart failure (HF) … postdischarge problem
among patients hospitalized for HF, the … patient outcomes substantially after HF hospitalization. …

… From a prospective multicentre multicountry clinical trial, we developed and validated risk
models to predict prospective all-cause mortality and hospitalizations because of heart failure (…