[HTML][HTML] Matching mechanism of death with mechanism of action: considerations for drug development for hospitalized heart failure

SJ Greene, M Gheorghiade - Journal of the American College of …, 2014 - jacc.org
… that outcome’s suspected mechanism of occurrence. A … events affecting hospitalized
patients with HF is needed. … Acute Heart Failure) trial, which randomized 1,161 hospitalized

Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods

A Ahmed, A Husain, TE Love, G Gambassi… - European heart …, 2006 - academic.oup.com
… In our matching algorithm, we first attempted to match each no-diuretic patient with a diuretic
… Then we removed those matched pairs of patients and repeated the process matching to …

Mode of Death After Acute Heart Failure Hospitalization–A Clue to Possible Mechanisms

KS Parikh, GM Felker, M Metra - Circulation Journal, 2015 - jstage.jst.go.jp
Heart failure continues to be a leading cause of hospitalization worldwide, and acute heart
failure … In this review, we will examine mortality during and after AHF hospitalization, with an …

Short-term survival by treatment among patients hospitalized with acute heart failure: the global ALARM-HF registry using propensity scoring methods

A Mebazaa, J Parissis, R Porcher, E Gayat… - Intensive care …, 2011 - Springer
Purpose To date, treatment with intravenous (IV) agents such as vasodilators, diuretics, and
inotropes has shown marginal or mixed benefits in acute heart failure (AHF) trials. The aim …

Effects of digoxin at low serum concentrations on mortality and hospitalization in heart failure: a propensity-matched study of the DIG trial

A Ahmed, B Pitt, SH Rahimtoola, F Waagstein… - International journal of …, 2008 - Elsevier
… on a propensity-matched cohort of heart failure patients suggest that digoxin in … cardiovascular
hospitalizations. Digoxin should be used in low doses to achieve low SDC in heart failure

Rehospitalization for heart failure: problems and perspectives

M Gheorghiade, M Vaduganathan, GC Fonarow… - Journal of the American …, 2013 - jacc.org
… Close to 1 million hospitalizations for heart failure (HHF) occur annually, accounting for over
6.5 million hospital days and a substantial portion of the estimated $37.2 billion that is spent …

Patterns of weight change preceding hospitalization for heart failure

SI Chaudhry, Y Wang, J Concato, TM Gill… - Circulation, 2007 - Am Heart Assoc
… patients with heart failure referred to a home monitoring system by … matched 134 case
patients with heart failure hospitalization to 134 control patients without heart failure hospitalization

Race and the natural history of chronic heart failure: a propensity-matched study

G Gambassi, SA Agha, X Sui, CW Yancy, J Butler… - … of cardiac failure, 2008 - Elsevier
hospitalization from worsening heart failure among nonwhite … a propensity-matched population
of heart failure patients in … for increased heart failure hospitalization among nonwhites, …

Heart failure-related hospitalization in the US, 1979 to 2004

J Fang, GA Mensah, JB Croft, NL Keenan - Journal of the American College …, 2008 - jacc.org
… , we assessed trends in hospitalizations for heart failure as either a first-listed or additional
(2nd to 7th) diagnosis. Among hospitalizations with any mention of heart failure, we assessed …

Chronic kidney disease associated mortality in diastolic versus systolic heart failure: a propensity matched study

A Ahmed, MW Rich, PW Sanders, GJ Perry… - The American journal of …, 2007 - Elsevier
… in heart failure (HF). However, it is unknown whether the effect of CKD on mortality varies
by left ventricular … We matched 2,399 pairs of patients with and without CKD with similar …