Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain
N Coppieters, BV Dieriks, C Lill, RLM Faull… - Neurobiology of …, 2014 - Elsevier
… All the brains received in the brain bank are routinely stained for Aβ, tau, and ubiquitin and
… A total of 29 neurologically normal and 29 AD postmortem human brains were used for this …
… A total of 29 neurologically normal and 29 AD postmortem human brains were used for this …
[HTML][HTML] DNA methylation signatures within the human brain
C Ladd-Acosta, J Pevsner, S Sabunciyan… - … Journal of Human …, 2007 - cell.com
… normal DNA methylation might distinguish individual brain regions. We determined the
quantitative DNA methylation … shown to be implicated in human cancer. We initially analyzed 76 …
quantitative DNA methylation … shown to be implicated in human cancer. We initially analyzed 76 …
Distinct DNA methylation changes highly correlated with chronological age in the human brain
… distinct brain regions, and furthermore, that the DNA methylation … of age on DNA methylation
status in human brain. We find that … between CpG methylation and aging of the human brain. …
status in human brain. We find that … between CpG methylation and aging of the human brain. …
Evolution of DNA methylation in the human brain
… the human brain. Here we have elucidated DNA methylation changes during recent human
brain … We demonstrate dynamic evolutionary trajectories of DNA methylation in cell-type and …
brain … We demonstrate dynamic evolutionary trajectories of DNA methylation in cell-type and …
Comprehensive DNA methylation and hydroxymethylation analysis in the human brain and its implication in mental disorders
… of the mouse and human brain (Lister et al., 2013). This study identified developmentally …
DNA methylation changes, and found that genome-wide reconfiguration of the DNA methylation …
DNA methylation changes, and found that genome-wide reconfiguration of the DNA methylation …
Genome-wide DNA methylation comparison between live human brain and peripheral tissues within individuals
… The use of surrogate tissues has become common in identifying methylation changes … as
surrogates for DNA methylation in the brain. Blood, saliva, buccal, and live brain tissue samples …
surrogates for DNA methylation in the brain. Blood, saliva, buccal, and live brain tissue samples …
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons
KD Siegmund, CM Connor, M Campan, TI Long… - PloS one, 2007 - journals.plos.org
… to confirm that the developmental DNA methylation changes as observed in this study are
a … of the human cerebral cortex. Furthermore, we monitored DNA methylation changes at a …
a … of the human cerebral cortex. Furthermore, we monitored DNA methylation changes at a …
Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients
LF Wockner, EP Noble, BR Lawford… - Translational …, 2014 - nature.com
… In this study, we analysed DNA methylation status in brain tissue, the primary tissue of …
methylation array with very extensive coverage of the potential methylation sites in the human …
methylation array with very extensive coverage of the potential methylation sites in the human …
DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease
… To determine if these genes underwent DNA methylation changes in the disorder, we
hybridized the frontal cortex samples from two well-established models of Alzheimer’s disease in …
hybridized the frontal cortex samples from two well-established models of Alzheimer’s disease in …
Aging effects on DNA methylation modules in human brain and blood tissue
… and DNA methylation levels and in brain and blood tissue. Third, we analyze four novel WB
DNA methylation … network analysis (WGCNA) of multiple methylation data sets. We apply the …
DNA methylation … network analysis (WGCNA) of multiple methylation data sets. We apply the …
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