DNA methylation in development and human disease

S Gopalakrishnan, BO Van Emburgh… - … Molecular Mechanisms of …, 2008 - Elsevier
development and carcinogenesis. In this review, we summarize the recent studies in DNA
methylation … role in gene silencing in development and disease. Although the molecular …

DNA methylation and human disease

KD Robertson - Nature Reviews Genetics, 2005 - nature.com
… patterns during embryonic development, … DNA methylation patterns in human diseases.
It should be noted that I focus only on those diseases for which defective DNA methylation

[HTML][HTML] DNA methylation in human diseases

Z Jin, Y Liu - Genes & diseases, 2018 - Elsevier
… is also related to the development and progression of many common diseases. Here, we first
… and mainly DNA methylation, in common human diseases. Introduction to DNA methylation

DNA methylation in mammalian development and disease

W Dean, D Lucifero, F Santos - Birth Defects Research Part C …, 2005 - Wiley Online Library
development and germ cell differentiation in humans will influence our understanding of the
potential impact of DNA methylation in human health and disease… focus on DNA methylation, …

The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… ESCs 117 , DNMT1-depleted human fibroblasts 118 , Dnmt3B-mutant mouse embryos 27,119
and human diseases linked with DNMT3B mutations 120 . What makes CGI promoters of …

DNA methylation 40 years later: Its role in human health and disease

MI Scarano, M Strazzullo, MR Matarazzo… - Journal of cellular …, 2005 - Wiley Online Library
… of human diseases caused by or involving DNA methylationdeveloped his hypothesis on
the role DNA methylation in the … relationship to gene silencing in disease. There is currently a …

[HTML][HTML] DNA methylation and histone deacetylation in the control of gene expression: basic biochemistry to human development and disease

A El-Osta, AP Wolffe - Gene expression, 2000 - ncbi.nlm.nih.gov
… , AND HUMAN DEVELOPMENT AND DISEASE Alterations in the controls of DNA methylation
and histone deacetylation have other profound roles in human disease. A common form of …

DNA methylation signatures in development and aging of the human prefrontal cortex

S Numata, T Ye, TM Hyde, X Guitart-Navarro… - … Journal of Human …, 2012 - cell.com
DNA methylation is strongly associated with genotypic variants and … development and in
de novo DNA methylation. Our results indicate that promoter DNA methylation in the human

[图书][B] DNA methylation: development, genetic disease and cancer

W Doerfler, P Böhm - 2006 - books.google.com
… In this volume, the 12 contributions written by experts in the fields of development,
genetic disease, and cancer biology deal with the role of DNA methylation in biology and …

DNA methylation in genomic imprinting, development, and disease

M Paulsen, AC Ferguson‐Smith - The Journal of pathology, 2001 - Wiley Online Library
… Changes in DNA methylation profiles are common features of development and in a
number of human diseases, such as cancer and imprinting disorders like Beckwith–Wiedemann …